{"id":"W4411241158","doi":"10.1080/21678421.2025.2515907","title":"Hospitalizations as an outcome measure in COURAGE-ALS","year":2025,"lang":"en","type":"article","venue":"Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; University of Alberta Hospital; University of Alberta; Montreal Neurological Institute and Hospital","funders":"Astellas Pharma","keywords":"Courage; Measure (data warehouse); Outcome (game theory); Psychology; Medicine; Computer science; Philosophy; Mathematics; Data mining; Mathematical economics; Theology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00581834,0.0004352427,0.0007613922,0.0007601188,0.0002586944,0.0006060075,0.000327663,0.0004022695,0.001437845],"category_scores_gemma":[0.008895298,0.0001114197,0.001014098,0.0006524856,0.0003497152,0.0006310533,0.0007625169,0.0008811716,0.0001041462],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000557542,"about_ca_system_score_gemma":0.0005600268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007893111,"about_ca_topic_score_gemma":0.001374196,"domain_scores_codex":[0.9956397,0.002541044,0.0005630164,0.0004070137,0.000699705,0.000149492],"domain_scores_gemma":[0.9892358,0.003821062,0.005441759,0.0003240434,0.000585422,0.0005919151],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0655635,0.00211928,0.8364604,0.001563218,0.002573114,0.0002444888,0.000723886,0.002926657,0.004291325,0.0005543677,0.001353181,0.08162661],"study_design_scores_gemma":[0.00162894,0.02382822,0.9651981,0.0001438791,0.0006013038,0.0003123244,0.0002686191,0.003621124,0.002320423,0.0004363227,0.001590409,0.00005037047],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925527,0.001795375,0.00226408,0.0001696413,0.00005472793,0.0004497514,0.00133175,0.00002914264,0.001352767],"genre_scores_gemma":[0.9957485,0.0003318645,0.001741395,0.0000572585,0.00005126773,0.0005642337,0.001150948,0.000005193584,0.0003494437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00581834,"threshold_uncertainty_score":0.03077066,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0401032148743357,"score_gpt":0.3162412589970621,"score_spread":0.2761380441227264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}