{"id":"W4411255039","doi":"10.1158/1557-3265.sabcs24-p2-08-26","title":"Abstract P2-08-26: FLEX: A Real-World Evidence, Full Transcriptome Study in 30,000 Patients with Early-Stage Breast Cancer","year":2025,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"FLEX; Cancer; Medicine; Transcriptome; Breast cancer; Stage (stratigraphy); Oncology; Internal medicine; Biology; Gene; Genetics; Computer science; Gene expression; Telecommunications","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004624664,0.0004824021,0.001062193,0.0008695729,0.001172945,0.001998314,0.001049071,0.001047313,0.006043112],"category_scores_gemma":[0.009641307,0.0005367955,0.001150509,0.002034223,0.0006514139,0.001281354,0.002022908,0.001380535,0.002460825],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009759464,"about_ca_system_score_gemma":0.001634151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003521438,"about_ca_topic_score_gemma":0.007091058,"domain_scores_codex":[0.9977927,0.00092109,0.0003451245,0.0005202797,0.0002560563,0.0001646438],"domain_scores_gemma":[0.9922616,0.001961103,0.001476972,0.001862597,0.001241448,0.001196242],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01385571,0.001538586,0.9039581,0.001903352,0.003350509,0.000894877,0.0009022346,0.0007629422,0.002756033,0.000998089,0.04116089,0.02791869],"study_design_scores_gemma":[0.003881105,0.002514322,0.9423711,0.00090588,0.002343627,0.001731817,0.00168739,0.00128273,0.0008912396,0.001659574,0.04056063,0.0001706002],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.833756,0.004616449,0.002527257,0.002839572,0.0001440132,0.001376035,0.1490917,0.0001343513,0.005514654],"genre_scores_gemma":[0.864522,0.001289131,0.004987448,0.003272834,0.0003043218,0.002903097,0.1207201,0.0001275832,0.001873363],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006043112,"threshold_uncertainty_score":0.02445787,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1665440028368959,"score_gpt":0.5251134407569966,"score_spread":0.3585694379201008,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}