{"id":"W4411263269","doi":"10.1016/j.dist.2025.100001","title":"Charting a new course in human health: Launching disease and therapeutics","year":2025,"lang":"en","type":"article","venue":"Disease and Therapeutics","topic":"Health, Environment, Cognitive Aging","field":"Environmental Science","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Course (navigation); Disease; Engineering ethics; Medicine; Engineering; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.019092,0.00162021,0.001999709,0.002131852,0.005383559,0.01673437,0.002689414,0.01311825,0.02294601],"category_scores_gemma":[0.01350783,0.0004889283,0.001200243,0.001187938,0.0202459,0.02452515,0.01029232,0.03005484,0.005015905],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.007540975,"about_ca_system_score_gemma":0.0313929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006921056,"about_ca_topic_score_gemma":0.01171067,"domain_scores_codex":[0.9933051,0.002628996,0.0004079644,0.0007151117,0.001874115,0.001068749],"domain_scores_gemma":[0.9764369,0.005719904,0.001214649,0.001491586,0.004518308,0.01061875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001536651,0.0004852783,0.001758863,0.0008037932,0.00003814986,0.0001899728,0.001935738,0.0004801404,0.001499951,0.2356858,0.6019867,0.1549819],"study_design_scores_gemma":[0.00005532747,0.0003398295,0.001237397,0.0007827234,0.00002350848,0.0001553113,0.002489859,0.0004473798,0.0003796186,0.1402128,0.8538029,0.00007338526],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.00168981,0.05833386,0.01003084,0.8591061,0.03848891,0.00009369008,0.0001455658,0.0003719501,0.03173911],"genre_scores_gemma":[0.1217548,0.1303724,0.06994633,0.4695693,0.08630983,0.0006067872,0.0005760699,0.0007814463,0.1200831],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.02294601,"threshold_uncertainty_score":0.1009693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02889771589462544,"score_gpt":0.3255734717428823,"score_spread":0.2966757558482568,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}