{"id":"W4411274746","doi":"10.1016/j.jbc.2025.109592","title":"Abstract 1428 Transactions across the border: Toxoplasma recruits mammalian ESCRT-III and ER Membrane Contact Site proteins at the parasitophorous vacuole to exploit host cell resources","year":2025,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Toxoplasma gondii Research Studies","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"ESCRT; Cell biology; Vacuole; Exploit; Biology; Host (biology); Membrane protein; Blacklist; Endosome; Membrane; Computer science; Genetics; Computer security; Cytoplasm; Intracellular","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001329385,0.0001936185,0.0002416594,0.0001219548,0.0002273516,0.0007504119,0.0001937868,0.0005318195,0.002982086],"category_scores_gemma":[0.0001795437,0.000109986,0.0001814399,0.0001148786,0.0002744309,0.0005447068,0.0005257933,0.0004251038,0.001682049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004148248,"about_ca_system_score_gemma":0.0002254226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005163089,"about_ca_topic_score_gemma":0.0005729407,"domain_scores_codex":[0.9998792,0.00001206758,0.000008288288,0.0000255215,0.00004741286,0.00002740515],"domain_scores_gemma":[0.9999012,0.000007004704,0.00002388602,0.00001472192,0.00002133988,0.0000319479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001140753,0.00001372283,0.001166745,0.00005542678,0.000006243356,0.0003134994,0.00004528222,0.00007895785,0.9942183,0.0008430472,0.0003013894,0.00284328],"study_design_scores_gemma":[0.00004664468,0.000235297,0.02685029,0.00005150107,0.00002101235,0.002243089,0.0004313512,0.004734115,0.9335501,0.0008375669,0.03098051,0.00001838742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9772943,0.003317345,0.00696816,0.0006560063,0.00008056593,0.0000237074,0.000286527,0.0001909111,0.01118234],"genre_scores_gemma":[0.9891466,0.0005425807,0.002694821,0.0001351012,0.0000104165,0.000006565685,0.0002687915,0.0000300198,0.007165291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002982086,"threshold_uncertainty_score":0.009976029,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01833511594487577,"score_gpt":0.2904217369841597,"score_spread":0.272086621039284,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}