{"id":"W4411294777","doi":"10.2337/db25-2003-lb","title":"2003-LB: An mRNA Immunotherapy for Type 1 Diabetes","year":2025,"lang":"en","type":"article","venue":"Diabetes","topic":"Hyperglycemia and glycemic control in critically ill and hospitalized patients","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Burnaby Hospital","funders":"","keywords":"Immunotherapy; Type 2 diabetes; Medicine; Messenger RNA; Immunology; Diabetes mellitus; Internal medicine; Biology; Endocrinology; Genetics; Immune system; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001417416,0.0005146008,0.0003030757,0.0004009832,0.0001660206,0.0004640186,0.0002858742,0.0005088118,0.00415303],"category_scores_gemma":[0.00006946346,0.00008944618,0.0003170206,0.0002313028,0.0002175042,0.0002534476,0.0002277491,0.0009421261,0.001618371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003176399,"about_ca_system_score_gemma":0.0003250526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003411776,"about_ca_topic_score_gemma":0.0003061517,"domain_scores_codex":[0.9998994,0.00001290997,0.000005931033,0.0000273419,0.00003323343,0.00002117783],"domain_scores_gemma":[0.9999692,0.000004349674,0.000008023502,0.000002784349,0.000005523324,0.00001017804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004439191,0.0003214302,0.0002124029,0.0002875421,0.00001681165,0.0001223712,0.00002054666,0.0002458439,0.9271715,0.0008842528,0.001610314,0.06866308],"study_design_scores_gemma":[0.0003569688,0.004175647,0.002326739,0.00007964132,0.000144268,0.001201634,0.00003215011,0.002048591,0.910825,0.000374701,0.07841561,0.00001903909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7941135,0.08409991,0.0598155,0.004105419,0.002789432,0.0007986844,0.002272315,0.002793807,0.04921153],"genre_scores_gemma":[0.8589417,0.03806026,0.03441161,0.001720687,0.0007227321,0.0005877065,0.002987479,0.000226077,0.06234189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00415303,"threshold_uncertainty_score":0.01389331,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01891538575214224,"score_gpt":0.3154758159735624,"score_spread":0.2965604302214201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}