{"id":"W4411306905","doi":"10.14740/wjon2571","title":"Immune Checkpoint Inhibition for Hepatocellular Carcinoma, Cholangiocarcinoma, and Combined Hepatocellular-Cholangiocarcinoma","year":2025,"lang":"en","type":"review","venue":"World Journal of Oncology","topic":"Cholangiocarcinoma and Gallbladder Cancer Studies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; Roswell Park Cancer Institute","keywords":"Medicine; Hepatocellular carcinoma; Immune system; Internal medicine; Cancer research; Immune checkpoint; Oncology; Gastroenterology; Immunotherapy; Immunology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004870879,0.0005817297,0.001267421,0.002343573,0.0002160042,0.0006153071,0.0005700217,0.0006578511,0.002920881],"category_scores_gemma":[0.000876636,0.000181021,0.0009451088,0.001865715,0.0002154875,0.0006232499,0.0004121087,0.0008520721,0.0006143329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000413204,"about_ca_system_score_gemma":0.001021376,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001202773,"about_ca_topic_score_gemma":0.002545978,"domain_scores_codex":[0.9998142,0.00003762706,0.00004385959,0.00002710887,0.0000636054,0.00001361003],"domain_scores_gemma":[0.9997284,0.0001502634,0.00005495792,0.000006080506,0.0000464778,0.00001383024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001346512,0.00007029574,0.0002570706,0.07016923,0.0003877658,0.000192272,0.00005942539,0.0002649715,0.0008946649,0.001313618,0.01704704,0.909209],"study_design_scores_gemma":[0.00008920365,0.0003109125,0.002657971,0.0323677,0.001817303,0.003080296,0.0001114697,0.0001603107,0.0007527042,0.001375762,0.9572447,0.00003170893],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008588497,0.9995246,0.00002314761,0.00006547494,0.00004190383,0.000003803742,0.00001177298,0.000002221737,0.0002412131],"genre_scores_gemma":[0.0006552803,0.9990119,0.00006212062,0.0000766028,0.00003682357,0.000005726726,0.00001935103,5.201199e-7,0.0001315831],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002920881,"threshold_uncertainty_score":0.009771347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04461970700246564,"score_gpt":0.3275489186285429,"score_spread":0.2829292116260773,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}