{"id":"W4411311524","doi":"10.1016/j.ccc.2025.05.001","title":"Pharmacology of Commonly Used Sedative Agents","year":2025,"lang":"en","type":"review","venue":"Critical Care Clinics","topic":"Intensive Care Unit Cognitive Disorders","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sinai Health System; Hôpital du Sacré-Cœur de Montréal; Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Sedative; Pharmacology; Anesthesia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002134331,0.0005079246,0.003385292,0.0003753065,0.00005998798,0.00000951591,0.0002920046,0.0007939994,0.0005490153],"category_scores_gemma":[0.03435151,0.0004562609,0.001350338,0.0004904183,0.0009017016,0.00003128246,0.0002433885,0.001393548,0.0001105592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000206995,"about_ca_system_score_gemma":0.001867706,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000336911,"about_ca_topic_score_gemma":0.000002446767,"domain_scores_codex":[0.9968245,0.0005955701,0.001224778,0.000590659,0.0003337643,0.0004307166],"domain_scores_gemma":[0.9771173,0.007558521,0.0002217151,0.0004591811,0.01441049,0.000232809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001074348,0.0003680626,0.00005912902,0.2059039,0.0008626341,0.0004916296,0.0003498029,3.061738e-8,6.578992e-7,0.001521241,0.03988475,0.7504507],"study_design_scores_gemma":[0.001031925,0.0006124238,0.000008620977,0.03036612,0.01131154,0.0000244966,0.003112202,0.000002325766,0.00001429032,0.00006431153,0.9531105,0.0003412765],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001194195,0.9796755,0.00008987803,0.0004157465,0.002473074,0.001514695,0.001146448,0.00005376865,0.0146189],"genre_scores_gemma":[0.0003541466,0.9849106,0.0001626529,0.01220068,0.0002587268,0.0001086759,0.001546996,0.00007494516,0.0003825864],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9132257,"threshold_uncertainty_score":0.9997889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1406097236277513,"score_gpt":0.5276519624358225,"score_spread":0.3870422388080712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}