{"id":"W4411314241","doi":"10.1111/febs.70156","title":"Epithelial cell shape changes contribute to regulation of ureteric bud branching morphogenesis","year":2025,"lang":"en","type":"article","venue":"FEBS Journal","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Helsinki Institute of Life Science, Helsingin Yliopisto; Biotieteiden ja Ympäristön Tutkimuksen Toimikunta; Biocenter Finland; Orionin Tutkimussäätiö; Munuaissäätiö; Lasten Syöpäsäätiö Väreen; Helsingin Yliopisto","keywords":"Morphogenesis; Cell biology; Branching (polymer chemistry); Biology; Ureteric bud; Actin; Cell division; Anatomy; Biophysics; Cell; Kidney development; Chemistry; Embryonic stem cell; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001484652,0.00008601834,0.0001228063,0.00007798152,0.00008479776,0.00001972015,0.0001204216,0.00010792,0.00003576856],"category_scores_gemma":[0.00002003596,0.00006996975,0.00008399668,0.000122744,0.00002041682,0.000002572822,0.00004087334,0.00008955398,0.000003678033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001992503,"about_ca_system_score_gemma":0.00006868385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007529488,"about_ca_topic_score_gemma":0.000005033429,"domain_scores_codex":[0.9994109,0.00004080995,0.0001719994,0.0001257849,0.00009865222,0.0001518166],"domain_scores_gemma":[0.9996153,0.000006117885,0.0001088038,0.0001014484,0.0001024347,0.00006594099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001769988,0.00001218152,0.0003134557,0.00001834746,0.00005857315,0.000002253461,0.00003175078,0.0008416917,0.9861358,0.00001005285,0.001807293,0.01059156],"study_design_scores_gemma":[0.0006065657,0.0002025847,0.005607915,0.00007756922,0.00003822662,0.00003308802,0.00002054804,0.000101935,0.9653516,0.00006913477,0.02779757,0.00009326731],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912789,0.00214013,0.004380634,0.0008243058,0.0005142951,0.00008230218,0.0000212987,0.000003787129,0.0007543339],"genre_scores_gemma":[0.9969394,0.0006532407,0.0003199137,0.0003924872,0.0003439378,0.000003158006,0.00001307278,0.00000792303,0.001326849],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02599028,"threshold_uncertainty_score":0.2853284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004756634918485991,"score_gpt":0.2269920678895932,"score_spread":0.2222354329711072,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}