{"id":"W4411314241","doi":"10.1111/febs.70156","title":"Epithelial cell shape changes contribute to regulation of ureteric bud branching morphogenesis","year":2025,"lang":"en","type":"article","venue":"FEBS Journal","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Helsinki Institute of Life Science, Helsingin Yliopisto; Biotieteiden ja Ympäristön Tutkimuksen Toimikunta; Biocenter Finland; Orionin Tutkimussäätiö; Munuaissäätiö; Lasten Syöpäsäätiö Väreen; Helsingin Yliopisto","keywords":"Morphogenesis; Cell biology; Branching (polymer chemistry); Biology; Ureteric bud; Actin; Cell division; Anatomy; Biophysics; Cell; Kidney development; Chemistry; Embryonic stem cell; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001269073,0.0002517541,0.0002288926,0.000256432,0.0003403182,0.0007941989,0.0001949594,0.0003497079,0.0006891956],"category_scores_gemma":[0.0002559261,0.0002236645,0.0002378615,0.000289384,0.0003916568,0.0003259295,0.0004102754,0.000363903,0.0003319976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004144793,"about_ca_system_score_gemma":0.0003166285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001097244,"about_ca_topic_score_gemma":0.0009586397,"domain_scores_codex":[0.9998428,0.00001856312,0.000009437073,0.00003048278,0.00006027474,0.00003842723],"domain_scores_gemma":[0.9998685,0.00001214531,0.00003976212,0.00001807042,0.00002928284,0.00003207514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007304421,0.00001586096,0.006672517,0.00006531862,0.000008166272,0.0003467357,0.0001055694,0.0007665411,0.9777866,0.0007922744,0.000194149,0.01317328],"study_design_scores_gemma":[0.00001813487,0.0001137502,0.3658096,0.00002960749,0.00003995755,0.001142183,0.0004307028,0.01936408,0.6028189,0.001835451,0.008351622,0.00004605402],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9778035,0.003958855,0.01309604,0.0002834826,0.0000373508,0.00002604725,0.000262445,0.0002275053,0.004304906],"genre_scores_gemma":[0.9963384,0.001213589,0.001412564,0.0000323269,0.000009387098,0.000011063,0.00009750325,0.00001688961,0.0008683853],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001097244,"threshold_uncertainty_score":0.003007233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004756634918485991,"score_gpt":0.2269920678895932,"score_spread":0.2222354329711072,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}