{"id":"W4411335038","doi":"10.1101/2025.06.13.659495","title":"Paralog interference preserves genetic redundancy","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Evolutionary Algorithms and Applications","field":"Computer Science","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; PROTEO","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Redundancy (engineering); Interference (communication); Computer science; Telecommunications","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007331255,0.0006816461,0.0008082084,0.0006254981,0.0004092047,0.0008797982,0.0007269806,0.0006381731,0.001537899],"category_scores_gemma":[0.002629333,0.0003318546,0.0003876555,0.0003591021,0.000623991,0.0008447068,0.001246986,0.0008149911,0.0005442639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005233318,"about_ca_system_score_gemma":0.0005294232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000236139,"about_ca_topic_score_gemma":0.0003110992,"domain_scores_codex":[0.9993782,0.0001283075,0.00003994038,0.0001588504,0.0001989387,0.00009570205],"domain_scores_gemma":[0.9981317,0.0006475354,0.0002835399,0.0006534558,0.000128761,0.0001550857],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0003703997,0.0001637749,0.01217659,0.0002104053,0.0001220857,0.001304836,0.000299044,0.05215161,0.845451,0.03589991,0.0006777498,0.05117261],"study_design_scores_gemma":[0.00009156998,0.001002482,0.02795465,0.00005264041,0.0002402945,0.006101523,0.0003025511,0.4923032,0.3603455,0.09437234,0.01712969,0.0001036656],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9225483,0.0002705566,0.0692312,0.0001618702,0.00003004951,0.00002127796,0.0001385297,0.0006406722,0.006957592],"genre_scores_gemma":[0.9916236,0.0001088776,0.007342396,0.00005490467,0.00000936722,0.00001781097,0.0000908016,0.00008470164,0.0006675532],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001537899,"threshold_uncertainty_score":0.005144775,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01650423017213794,"score_gpt":0.2346478460983082,"score_spread":0.2181436159261703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}