{"id":"W4411371017","doi":"10.1016/j.ijregi.2025.100685","title":"Real-world effectiveness, safety, and health-related quality of life in people living with HIV receiving bictegravir/emtricitabine/tenofovir alafenamide—12-month results of the BICSTaR French cohort","year":2025,"lang":"en","type":"article","venue":"IJID Regions","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Centers for Disease Control and Prevention; Académie canadienne du génie; Gilead Sciences","keywords":"Emtricitabine; Tenofovir alafenamide; Tenofovir; Human immunodeficiency virus (HIV); Medicine; Quality of life (healthcare); Gerontology; Virology; Antiretroviral therapy; Viral load; Nursing","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002062777,0.0004098405,0.0004540672,0.0008318523,0.0005087102,0.0009486037,0.0003491647,0.0005958828,0.00132716],"category_scores_gemma":[0.00273098,0.0002460911,0.001041317,0.0007013161,0.000263947,0.000543871,0.0005326411,0.0005572376,0.0002932509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008397983,"about_ca_system_score_gemma":0.0004287055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01979922,"about_ca_topic_score_gemma":0.0163197,"domain_scores_codex":[0.9992119,0.0003225993,0.00006068535,0.0001180509,0.0001209921,0.0001657381],"domain_scores_gemma":[0.9983717,0.0002160906,0.0007336561,0.0001036828,0.0002399999,0.0003349074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006771482,0.0001011599,0.9972963,0.0000110168,0.0001535422,0.00003352217,0.00009900099,0.00005300915,0.00007401514,0.000004459739,0.0001325309,0.001364201],"study_design_scores_gemma":[0.00003463302,0.0004793637,0.9988556,0.000007433776,0.00006127499,0.00007397175,0.0001660613,0.0001211134,0.00002728163,0.000004414298,0.0001629986,0.000005750598],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998857,0.0001946467,0.00002383165,0.00002374435,0.000003638832,0.00001196403,0.0007201913,0.000001876101,0.0001630835],"genre_scores_gemma":[0.9986655,0.00008151941,0.00003897217,0.00003277714,0.000008519358,0.00001626717,0.001010007,0.000001471012,0.0001449957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01979922,"threshold_uncertainty_score":0.03936791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01703351714735733,"score_gpt":0.2806934782747568,"score_spread":0.2636599611273994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}