{"id":"W4411373268","doi":"10.1017/s0033291725000765","title":"Novel tools for comparing the architecture of psychopathology between neurogenetic disorders: An application to X- versus Y-chromosome aneuploidy effects in males","year":2025,"lang":"en","type":"article","venue":"Psychological Medicine","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of General Medical Sciences; National Institute of Mental Health; National Institutes of Health","keywords":"Psychopathology; Psychology; Autism; Genetic architecture; Clinical psychology; Aneuploidy; Psychiatry; Genetics; Chromosome; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004804108,0.0001468566,0.0003495154,0.00007970578,0.00005392846,0.000003915175,0.0003466945,0.0001882435,0.000002317283],"category_scores_gemma":[0.001175881,0.00009873722,0.00005599163,0.0002388354,0.0001813192,0.000001823963,0.00006379094,0.0001285172,0.000001148404],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009078029,"about_ca_system_score_gemma":0.000006340868,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001924553,"about_ca_topic_score_gemma":0.0001282268,"domain_scores_codex":[0.998687,0.0001715115,0.0003651082,0.0004530281,0.00006700906,0.0002563378],"domain_scores_gemma":[0.9987947,0.0005689583,0.0001058257,0.0004274088,0.00004228273,0.00006086717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0008286657,0.0004382858,0.2194748,0.00007839001,0.00007287223,5.438606e-7,0.0001657093,0.002623794,0.6220435,0.001057201,0.0004057823,0.1528105],"study_design_scores_gemma":[0.002439237,0.002592194,0.9898286,0.00002420906,0.00004117616,0.000002578664,0.00006262156,0.0001519025,0.0007602851,0.002024557,0.001966588,0.0001060646],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8537825,0.0002908744,0.1405727,0.004062218,0.0002337191,0.0007757056,0.000009590589,0.000008470286,0.0002641307],"genre_scores_gemma":[0.9946986,0.00005096187,0.003484309,0.001119982,0.000210033,0.0003082763,0.0001054138,0.000009345781,0.00001302347],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7703538,"threshold_uncertainty_score":0.4026387,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04302424827088499,"score_gpt":0.372319210213286,"score_spread":0.329294961942401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}