{"id":"W4411373268","doi":"10.1017/s0033291725000765","title":"Novel tools for comparing the architecture of psychopathology between neurogenetic disorders: An application to X- versus Y-chromosome aneuploidy effects in males","year":2025,"lang":"en","type":"article","venue":"Psychological Medicine","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of General Medical Sciences; National Institute of Mental Health; National Institutes of Health","keywords":"Psychopathology; Psychology; Autism; Genetic architecture; Clinical psychology; Aneuploidy; Psychiatry; Genetics; Chromosome; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002638661,0.0008921837,0.0004990216,0.005492881,0.0006775299,0.001477333,0.0005358311,0.0004194643,0.008576083],"category_scores_gemma":[0.01101563,0.0002898302,0.0013939,0.002701243,0.0008131593,0.0008445426,0.001769831,0.0013773,0.0006269738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005116586,"about_ca_system_score_gemma":0.0007117263,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002300729,"about_ca_topic_score_gemma":0.003918803,"domain_scores_codex":[0.998704,0.0005371076,0.0001073185,0.0003386552,0.0002359784,0.00007699102],"domain_scores_gemma":[0.9934331,0.003617848,0.001296537,0.0008148243,0.0004307172,0.0004069417],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.001115824,0.0003837523,0.5201583,0.0006146841,0.002500245,0.000912105,0.003022911,0.008624415,0.1028642,0.01948324,0.006380163,0.3339402],"study_design_scores_gemma":[0.0001101133,0.0007175675,0.8652551,0.0001539994,0.0004280372,0.001457816,0.00186194,0.08022523,0.01162429,0.03009057,0.00792097,0.0001544801],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.448358,0.0007419268,0.5344207,0.0007902441,0.0001080692,0.0003954728,0.006702721,0.0034901,0.00499271],"genre_scores_gemma":[0.7000211,0.0002291595,0.2955657,0.0001312934,0.00007712607,0.000630562,0.001867354,0.0003562871,0.001121487],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.008576083,"threshold_uncertainty_score":0.02868992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04302424827088499,"score_gpt":0.372319210213286,"score_spread":0.329294961942401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}