{"id":"W4411381470","doi":"10.1016/j.ijbiomac.2025.145347","title":"The mechanism of IGF-AKT pathway promoting mantle biomineralization in Hyriopsis cumingii","year":2025,"lang":"en","type":"article","venue":"International Journal of Biological Macromolecules","topic":"Calcium Carbonate Crystallization and Inhibition","field":"Materials Science","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ministry of Agriculture","funders":"National Key Research and Development Program of China; Earmarked Fund for China Agriculture Research System; National Natural Science Foundation of China","keywords":"Biomineralization; Mantle (geology); Mechanism (biology); Chemistry; Protein kinase B; Geochemistry; Biology; Geology; Astrobiology; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005577791,0.0002268378,0.0001894739,0.0002022015,0.000312073,0.0002925358,0.0002911915,0.0003411932,0.0007092634],"category_scores_gemma":[0.00004365008,0.0001307445,0.0003422656,0.0001242444,0.0002068112,0.0003532365,0.0003158648,0.0004165415,0.0001895724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004940946,"about_ca_system_score_gemma":0.0004175174,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007598692,"about_ca_topic_score_gemma":0.007071807,"domain_scores_codex":[0.9999543,0.000002076693,0.000003836028,0.00001311792,0.00001028759,0.0000163855],"domain_scores_gemma":[0.9999667,0.000004434497,0.000008799105,0.000004276869,0.000006879296,0.000008790903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005445502,0.000004709272,0.0003587282,0.00004330516,0.000002305717,0.00005877657,0.0000114488,0.0000718639,0.9983675,0.000246153,0.00003492827,0.000745784],"study_design_scores_gemma":[0.00002451842,0.00009283829,0.04807052,0.0000140935,0.00003030776,0.0002682269,0.0002279045,0.00361239,0.9417466,0.0004130136,0.005478468,0.00002114034],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863449,0.003426159,0.002857565,0.0003416175,0.000044262,0.00002694709,0.001121653,0.000170639,0.005666322],"genre_scores_gemma":[0.9953616,0.0004708418,0.0007823802,0.00005480628,0.000003222293,0.00001062543,0.0002973647,0.000008505439,0.003010647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007598692,"threshold_uncertainty_score":0.01510894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01327376940516652,"score_gpt":0.2702542463772887,"score_spread":0.2569804769721222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}