{"id":"W4411389936","doi":"10.1101/2025.06.11.659140","title":"Transgenic Inducible MHC I Overexpression in Mouse Alveolar Type 2 Cells","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Genetically modified mouse; Transgene; Cell biology; Biology; Major histocompatibility complex; Molecular biology; Immunology; Antigen; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000459217,0.0005643053,0.0003175003,0.0005365338,0.0001942533,0.0004389163,0.0004847853,0.0005242117,0.001715678],"category_scores_gemma":[0.0001182693,0.0002187214,0.0003858471,0.0002997241,0.0003470677,0.0002707274,0.0003750927,0.001066037,0.001168086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003723085,"about_ca_system_score_gemma":0.000179966,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004887857,"about_ca_topic_score_gemma":0.0005935299,"domain_scores_codex":[0.9994422,0.00009766717,0.00005034605,0.0001341211,0.0001606803,0.00011488],"domain_scores_gemma":[0.9997482,0.00004102621,0.0000722929,0.00004825626,0.00002661416,0.00006357404],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004262005,0.00001681151,0.0000578862,0.00001543722,0.000002194377,0.00004747089,0.00001104399,0.00005246331,0.9991868,0.000173268,0.00003795187,0.0003560665],"study_design_scores_gemma":[0.00001511282,0.0001285,0.0007833887,0.000005022009,0.000007916598,0.0001898491,0.00001704529,0.0008435296,0.994149,0.00005017119,0.003806251,0.00000416055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9397774,0.001933479,0.04752988,0.0003596088,0.0002192102,0.0002634781,0.002929185,0.0007752453,0.006212534],"genre_scores_gemma":[0.9562246,0.0009855171,0.018708,0.0001346365,0.00005812879,0.0002503551,0.00214991,0.0002444292,0.02124453],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001715678,"threshold_uncertainty_score":0.00573957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01387273018234645,"score_gpt":0.2243313293658563,"score_spread":0.2104585991835098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}