{"id":"W4411395530","doi":"10.1016/j.ard.2025.05.388","title":"LB0001 EFFICACY AND SAFETY OF DEUCRAVACITINIB UP TO WEEK 16 FROM POETYK PsA-1: A MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PHASE 3 STUDY IN PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS","year":2025,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's College Hospital; University of Toronto","funders":"","keywords":"Medicine; Psoriatic arthritis; Placebo; Double blind; Multicenter study; Internal medicine; Arthritis; Randomized controlled trial; Dermatology; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00221985,0.001523321,0.002992766,0.0005651828,0.0008166011,0.001237768,0.001019008,0.001986821,0.006496598],"category_scores_gemma":[0.001257363,0.0007554156,0.002337124,0.0005207064,0.001335564,0.001486429,0.0004850902,0.004151681,0.00143079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008505535,"about_ca_system_score_gemma":0.001669896,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000542754,"about_ca_topic_score_gemma":0.001647138,"domain_scores_codex":[0.9990366,0.0003708937,0.00009521804,0.0001999141,0.0001399378,0.0001574828],"domain_scores_gemma":[0.9989566,0.0001488962,0.0003311376,0.00007976886,0.00009177383,0.0003917119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8920204,0.04264573,0.002982038,0.001112225,0.001397372,0.00008939688,0.0001364818,0.0006342438,0.01567397,0.00008409087,0.001739868,0.0414841],"study_design_scores_gemma":[0.7746399,0.2141045,0.007589997,0.00003271508,0.0004922403,0.0001198403,0.00002228832,0.0003553757,0.001486947,0.00007722293,0.001051113,0.00002794027],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848548,0.005224516,0.0007129142,0.0004380069,0.0002680387,0.004905003,0.001531341,0.0001816797,0.001883624],"genre_scores_gemma":[0.9894615,0.001513217,0.001227395,0.0007412748,0.0002906237,0.003112328,0.001780191,0.00002899823,0.001844514],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006496598,"threshold_uncertainty_score":0.02173334,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02808955022993623,"score_gpt":0.3389888916707877,"score_spread":0.3108993414408514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}