{"id":"W4411395530","doi":"10.1016/j.ard.2025.05.388","title":"LB0001 EFFICACY AND SAFETY OF DEUCRAVACITINIB UP TO WEEK 16 FROM POETYK PsA-1: A MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PHASE 3 STUDY IN PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS","year":2025,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's College Hospital; University of Toronto","funders":"","keywords":"Medicine; Psoriatic arthritis; Placebo; Double blind; Multicenter study; Internal medicine; Arthritis; Randomized controlled trial; Dermatology; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005770834,0.0002769602,0.001829281,0.0003157027,0.00009583516,0.0000279068,0.0002691641,0.00005355424,0.0001399742],"category_scores_gemma":[0.001935194,0.0001712402,0.0002443376,0.00041604,0.0002652906,0.0001526482,0.0001746423,0.0001673039,0.000005701167],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003165326,"about_ca_system_score_gemma":0.0002977504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006090816,"about_ca_topic_score_gemma":0.00009399594,"domain_scores_codex":[0.9970218,0.0005246591,0.00119029,0.000327708,0.0006178858,0.0003176811],"domain_scores_gemma":[0.9971331,0.001332032,0.0004366837,0.0005983523,0.0003415358,0.0001582529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9034017,0.007374834,0.01299507,0.0002750865,0.001977856,0.000002920062,0.002992205,0.00002386273,0.000002597945,0.00004802702,0.0002045939,0.0707012],"study_design_scores_gemma":[0.8869843,0.001015523,0.1037357,0.003488765,0.0005881403,1.785224e-7,0.003466442,0.0002135706,0.0001449662,0.0001983384,0.00001910472,0.000144893],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863502,0.001604405,0.00005926047,0.0006527959,0.00008687904,0.01080821,0.0001363125,0.00001639534,0.0002855666],"genre_scores_gemma":[0.9985378,0.000537314,0.00002445158,0.000150825,0.000007163378,0.0004900997,0.00004305658,0.00002118249,0.0001881522],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09074068,"threshold_uncertainty_score":0.6982973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02808955022993623,"score_gpt":0.3389888916707877,"score_spread":0.3108993414408514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}