{"id":"W4411399861","doi":"10.1016/j.ajpath.2025.05.017","title":"Distinct Role of Dural and Leptomeningeal Macrophages in Maintaining Cerebrospinal Fluid Drainage to Meningeal Lymphatic Vessels","year":2025,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Cerebrospinal fluid and hydrocephalus","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Leptomeninges; Meninges; Cerebrospinal fluid; Dura mater; Pia mater; Pathology; Medicine; Lymphatic system; Cisterna magna; Glymphatic system; Macrophage; Subarachnoid space; Infiltration (HVAC); Central nervous system; Anatomy; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001539051,0.0002083542,0.0001801927,0.0002690602,0.0001930653,0.0003787056,0.0001733245,0.0002720662,0.0004340945],"category_scores_gemma":[0.000154389,0.00008567847,0.0001351584,0.00008117491,0.0003570596,0.0004473949,0.0002616626,0.0002468647,0.000162008],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001972426,"about_ca_system_score_gemma":0.0003719548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006436249,"about_ca_topic_score_gemma":0.0009463505,"domain_scores_codex":[0.9998707,0.00002390924,0.00001065429,0.00001868662,0.00002020883,0.00005589643],"domain_scores_gemma":[0.9999214,0.000007722781,0.00001648386,0.000007366445,0.00001769214,0.00002932729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005668804,0.00005891052,0.002885714,0.000116846,0.000009668273,0.0004984814,0.0001260206,0.00003509628,0.9869723,0.0009402246,0.00005723913,0.007732687],"study_design_scores_gemma":[0.0001673412,0.001369316,0.1026679,0.0001136481,0.0001188506,0.003545042,0.001585018,0.001224698,0.8767723,0.001097484,0.01130091,0.00003747118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913907,0.005321116,0.001504033,0.0001041929,0.00002582638,0.00002765829,0.00007537413,0.00001168484,0.001539332],"genre_scores_gemma":[0.9951776,0.001993305,0.001229976,0.00003326726,0.00001185554,0.00003221846,0.00006294452,0.000003152516,0.001455618],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006436249,"threshold_uncertainty_score":0.001452208,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007256305742331667,"score_gpt":0.2736490675521613,"score_spread":0.2663927618098296,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}