{"id":"W4411400707","doi":"10.1016/j.ard.2025.06.505","title":"POS1155 IMPROVEMENT OF FATIGUE IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS TREATED WITH DAPIROLIZUMAB PEGOL: 48-WEEK RESULTS FROM A PHASE 3 TRIAL","year":2025,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Medicine; Certolizumab pegol; Internal medicine; Lupus erythematosus; Immunology; Rheumatoid arthritis; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003147737,0.001649128,0.002921917,0.0004220752,0.0005650481,0.001372811,0.0009770837,0.00242982,0.006451464],"category_scores_gemma":[0.002073094,0.0005634691,0.003159423,0.0004580996,0.001103525,0.001088513,0.0004877439,0.002968096,0.001201842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009199178,"about_ca_system_score_gemma":0.001013658,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007952406,"about_ca_topic_score_gemma":0.00171875,"domain_scores_codex":[0.9991148,0.0004780031,0.00005596342,0.0001123083,0.00008207026,0.000156788],"domain_scores_gemma":[0.9986182,0.0003395095,0.0003321265,0.0001019923,0.0001014362,0.000506747],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9546826,0.009670701,0.00115959,0.001090349,0.001347092,0.0001149298,0.0001385652,0.00053833,0.00422635,0.00008554339,0.001600593,0.02534527],"study_design_scores_gemma":[0.8527728,0.1408036,0.004310569,0.00007900694,0.0004620393,0.00008142235,0.00003351891,0.0002228605,0.0002731432,0.00009749665,0.0008392219,0.0000243395],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9761364,0.01042833,0.0007704326,0.001053052,0.0004305629,0.004998492,0.002652663,0.0002113264,0.003318684],"genre_scores_gemma":[0.9813623,0.004590947,0.001262508,0.00213936,0.0004298196,0.005094324,0.002666635,0.00003869287,0.002415332],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006451464,"threshold_uncertainty_score":0.02158231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03665279749404277,"score_gpt":0.3198288032195787,"score_spread":0.283176005725536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}