{"id":"W4411410168","doi":"10.1016/j.ard.2025.06.1415","title":"ABS0974 EARLY IMPROVEMENTS IN CLINICAL DISEASE ACTIVITY INDEX FOR PSORIATIC ARTHRITIS AND ITS COMPONENTS WITH GUSELKUMAB PREDICT CLINICAL RESPONSE IN TNFi-EXPERIENCED AND BIOLOGIC-NAÏVE PARTICIPANTS WITH ACTIVE PSORIATIC ARTHRITIS: POST HOC ANALYSES OF THREE PHASE 3, RANDOMIZED, CONTROLLED STUDIES","year":2025,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; Psoriatic arthritis; Psoriasis; Dermatology; Arthritis; Clinical trial; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01810589,0.001522148,0.003719398,0.0008563505,0.0004647045,0.001568432,0.000884979,0.001044671,0.003928031],"category_scores_gemma":[0.01445031,0.0006061947,0.01073971,0.001246916,0.001102465,0.001159256,0.0007819683,0.001882195,0.000414236],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007228833,"about_ca_system_score_gemma":0.001727606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005967953,"about_ca_topic_score_gemma":0.002215795,"domain_scores_codex":[0.9904174,0.006059622,0.001272068,0.0008894343,0.0009214987,0.0004398944],"domain_scores_gemma":[0.9853182,0.007848927,0.004052693,0.001081047,0.001050377,0.0006488569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.894457,0.001912203,0.01555565,0.004065558,0.06370807,0.00003095704,0.00008205602,0.0006642277,0.002064564,0.000103141,0.0004893198,0.01686726],"study_design_scores_gemma":[0.5285923,0.1409401,0.1168947,0.0007799026,0.2039329,0.000173839,0.0001490006,0.002076498,0.002871691,0.0006953639,0.002775519,0.0001181578],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9567632,0.02913363,0.002476297,0.0004380543,0.0004674264,0.005013814,0.003439272,0.0001270882,0.002141323],"genre_scores_gemma":[0.9890711,0.003616372,0.001880979,0.000288741,0.0002555163,0.003093837,0.0012089,0.00002347176,0.0005611322],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01810589,"threshold_uncertainty_score":0.09575427,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.118667328043004,"score_gpt":0.4566904498972508,"score_spread":0.3380231218542468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}