{"id":"W4411425692","doi":"10.1016/j.ard.2025.06.778","title":"POS1431 CIRCULATING CD14+ MONOCYTES DISPLAY A PRO-MIGRATORY AND PRO-INFLAMMATORY PHENOTYPE IN INTERSTITIAL LUNG DISEASE ASSOCIATED WITH RHEUMATOID ARTHRITIS","year":2025,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Rheumatoid arthritis; Interstitial lung disease; CD14; Phenotype; Immunology; Lung; Arthritis; Inflammation; Pathology; Internal medicine; Immune system; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001703915,0.0001886969,0.0003075806,0.000412928,0.0003476683,0.0003333693,0.0001589274,0.0002971182,0.002541686],"category_scores_gemma":[0.0005275016,0.0001170794,0.0001368054,0.0004160843,0.0001946275,0.000115278,0.0002653808,0.0002044632,0.000494957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009733671,"about_ca_system_score_gemma":0.0001090996,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004642989,"about_ca_topic_score_gemma":0.0005621125,"domain_scores_codex":[0.9998072,0.00003626252,0.00003210968,0.00005208294,0.00003782655,0.00003468599],"domain_scores_gemma":[0.9997712,0.00004794529,0.00007890705,0.0000139085,0.0000367254,0.00005137176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001886277,0.0001473629,0.9571528,0.0001268118,0.00002744015,0.001530088,0.0003046987,0.00008488066,0.0285082,0.00003732038,0.0002358901,0.009958383],"study_design_scores_gemma":[0.00002952817,0.0006833762,0.9933289,0.0000153863,0.00002922574,0.003431052,0.0002908697,0.0001346929,0.001474316,0.00004594825,0.0005315656,0.000005159111],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990461,0.0003586685,0.0001269914,0.00001216743,0.000005421557,0.00001548127,0.0001602462,0.000002791473,0.0002719701],"genre_scores_gemma":[0.999019,0.0001212937,0.0002445437,0.00003136318,0.00002106124,0.0000308395,0.0002883573,0.000001325353,0.0002420557],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002541686,"threshold_uncertainty_score":0.008502781,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01089239156590277,"score_gpt":0.2596663408712913,"score_spread":0.2487739493053885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}