{"id":"W4411432922","doi":"10.1016/j.ard.2025.06.077","title":"POS0717 VALIDATION OF ANTI-14-3-3? (ETA) MULTIPLEX LABORATORY DEVELOPED TEST (LDT) FOR THE DIAGNOSIS OF AXIAL SPONDYLOARTHRITIS (axSpA)","year":2025,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Axial spondyloarthritis; Multiplex; Test (biology); Ankylosing spondylitis; Medical physics; Internal medicine; Physical therapy; Bioinformatics; Sacroiliitis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002175627,0.0001290211,0.0002387463,0.00005503592,0.0001051156,0.00001460962,0.0004036625,0.0000660499,0.00002999847],"category_scores_gemma":[0.004815336,0.00009083945,0.0002393887,0.0002069159,0.000206582,0.00001229654,0.0001400711,0.00004145545,0.000001252253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004954648,"about_ca_system_score_gemma":0.0002278697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007099977,"about_ca_topic_score_gemma":0.00002712568,"domain_scores_codex":[0.998982,0.0001006177,0.0004447619,0.0001696831,0.0001609781,0.0001420326],"domain_scores_gemma":[0.9979522,0.0005521132,0.000335508,0.0005348303,0.0005930077,0.00003239924],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001083826,0.003828889,0.2941873,0.003527148,0.003204018,0.00000117501,0.0005692511,0.002813264,0.4934301,0.001600278,0.1130011,0.08275361],"study_design_scores_gemma":[0.0005358614,0.0001231097,0.09717222,0.0005469234,0.0001298316,5.226435e-7,0.000127524,0.00009418553,0.8970422,0.0002950646,0.003829454,0.0001031638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931278,0.002873846,0.0003598793,0.001283558,0.0002510975,0.0007262409,0.001303313,0.000006870296,0.00006740314],"genre_scores_gemma":[0.9979251,0.001160348,0.0002409393,0.000154164,0.00003123843,0.0002359791,0.00006881547,0.00001370554,0.0001696974],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.403612,"threshold_uncertainty_score":0.5764755,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02836522890630178,"score_gpt":0.3200688398195898,"score_spread":0.2917036109132881,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}