{"id":"W4411437072","doi":"10.1016/j.jtct.2025.06.015","title":"Impact of Abatacept Inclusive Graft-Versus-Host Disease Prophylaxis in Pediatric Stem Cell Transplantation for Hemoglobinopathy","year":2025,"lang":"en","type":"article","venue":"Transplantation and Cellular Therapy","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital Research Institute of Manitoba","funders":"Children's Discovery Institute","keywords":"Medicine; Abatacept; Prednisone; Internal medicine; Transplantation; Hematopoietic stem cell transplantation; Graft-versus-host disease; Rituximab; Surgery; Immunology; Lymphoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003775184,0.0001494271,0.0002742943,0.00008861672,0.0001118235,0.0002333827,0.0001171308,0.0001405735,0.0005730437],"category_scores_gemma":[0.0005843003,0.00005169977,0.0002202239,0.00008180574,0.0001567616,0.0001848817,0.0001352142,0.000377709,0.00005432764],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002366486,"about_ca_system_score_gemma":0.0004135705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003816658,"about_ca_topic_score_gemma":0.0009371928,"domain_scores_codex":[0.9998224,0.00007648282,0.00001694676,0.00001958531,0.00003264226,0.00003189629],"domain_scores_gemma":[0.999645,0.0001155187,0.00008410872,0.00001449279,0.00001477979,0.0001260966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.08313125,0.008884131,0.3360078,0.0006421502,0.0005627119,0.003033093,0.0005033641,0.004861127,0.05253231,0.0004946362,0.001185754,0.5081617],"study_design_scores_gemma":[0.004579624,0.2032533,0.7559393,0.0002689819,0.0008839114,0.006463298,0.0003719339,0.004030382,0.02014116,0.0002802089,0.003762256,0.00002562156],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990425,0.0007174682,0.00003963118,0.00001511734,0.000005897281,0.000005104348,0.000008971996,0.000003047358,0.000162176],"genre_scores_gemma":[0.9995723,0.0002311786,0.00008935889,0.00002298601,0.000008002973,0.000004831556,0.00002873304,7.274933e-7,0.00004179301],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005730437,"threshold_uncertainty_score":0.001996517,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01234951854423958,"score_gpt":0.2811436709245076,"score_spread":0.268794152380268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}