{"id":"W4411437072","doi":"10.1016/j.jtct.2025.06.015","title":"Impact of Abatacept Inclusive Graft-Versus-Host Disease Prophylaxis in Pediatric Stem Cell Transplantation for Hemoglobinopathy","year":2025,"lang":"en","type":"article","venue":"Transplantation and Cellular Therapy","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital Research Institute of Manitoba","funders":"Children's Discovery Institute","keywords":"Medicine; Abatacept; Prednisone; Internal medicine; Transplantation; Hematopoietic stem cell transplantation; Graft-versus-host disease; Rituximab; Surgery; Immunology; Lymphoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002342255,0.0002807055,0.0004092655,0.0004523142,0.00008194002,0.00001849931,0.0000879966,0.000147732,0.00002938882],"category_scores_gemma":[0.000002953383,0.0002493102,0.0002147692,0.0004897401,0.00005836061,0.0001368686,0.000002954452,0.0001425832,0.000003009143],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007891242,"about_ca_system_score_gemma":0.0002879276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006063047,"about_ca_topic_score_gemma":0.000019557,"domain_scores_codex":[0.9983958,0.0001018876,0.000569508,0.0003982791,0.0002631002,0.0002714384],"domain_scores_gemma":[0.999145,0.0002467376,0.0001360473,0.0001995525,0.0001220443,0.0001506013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1212296,0.002461963,0.4369928,0.02539247,0.0004142116,0.0004446648,0.02814433,0.0004271363,0.3620529,0.001377825,0.00003875981,0.0210234],"study_design_scores_gemma":[0.04777439,0.003401429,0.6769741,0.0005921575,0.001175501,0.00002632905,0.0007073217,0.0007182801,0.2677453,0.0002330414,0.00005033805,0.0006018644],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9781064,0.001873869,0.01700069,0.00009721115,0.0001478088,0.001928611,0.0003010537,0.0000448492,0.0004995298],"genre_scores_gemma":[0.9870959,0.01157729,0.0003079617,0.00004781994,0.00003728836,0.0001303249,0.0006409199,0.0000299957,0.0001324844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2399813,"threshold_uncertainty_score":0.9999959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01234951854423958,"score_gpt":0.2811436709245076,"score_spread":0.268794152380268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}