{"id":"W4411439572","doi":"10.1016/j.cjca.2025.06.008","title":"The Trials of Interpreting Clinical Trials—A Bayesian Perspective on Colchicine After an Acute Coronary Syndrome","year":2025,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Mace; Prior probability; Randomized controlled trial; Myocardial infarction; Bayesian probability; Internal medicine; Credible interval; Revascularization; Clinical trial; Relative risk; Meta-analysis; Cardiology; Confidence interval; Conventional PCI; Statistics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.5213285,0.003912271,0.01900453,0.00733717,0.00341186,0.01862324,0.01076909,0.02974049,0.007135191],"category_scores_gemma":[0.8042185,0.0043975,0.005696376,0.006322769,0.04683529,0.02039721,0.006941001,0.03787716,0.0008485799],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01245975,"about_ca_system_score_gemma":0.01370105,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01174077,"about_ca_topic_score_gemma":0.008921738,"domain_scores_codex":[0.3722118,0.5869237,0.01681602,0.01056201,0.01206273,0.001423772],"domain_scores_gemma":[0.03820974,0.9376851,0.01017958,0.0071989,0.004799278,0.00192737],"domain_codex":"methods","domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.004126216,0.0002274164,0.008286711,0.008487821,0.01079682,0.001529587,0.00240201,0.04866585,0.0002597334,0.723809,0.04958886,0.14182],"study_design_scores_gemma":[0.0009021557,0.0001609002,0.0006277164,0.003401107,0.0009422309,0.0003210713,0.0001745494,0.01910297,0.0001205852,0.962005,0.01209806,0.0001437158],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.005291919,0.121255,0.1626016,0.6903531,0.008166386,0.0004661205,0.0007952965,0.0001604026,0.01091024],"genre_scores_gemma":[0.4447603,0.07990492,0.2182272,0.1789379,0.06919405,0.003706825,0.0007132142,0.0004457718,0.00410983],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.5213285,"threshold_uncertainty_score":0.5902872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02302862363257816,"score_gpt":0.3622294616694281,"score_spread":0.3392008380368499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}