{"id":"W4411464422","doi":"10.3389/fimmu.2025.1613719","title":"Tumor necrosis factor receptor 2 in allergen tolerance: a perspective view","year":2025,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Allergic Rhinitis and Sensitization","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"HORIZON EUROPE Framework Programme; European Academy of Allergy and Clinical Immunology; Fonds National de la Recherche Luxembourg","keywords":"Perspective (graphical); Tumor necrosis factor alpha; Tumor necrosis factor receptor; Allergen; Immunology; Receptor; Medicine; Cancer research; Allergy; Internal medicine; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004806082,0.0007413847,0.0008677999,0.001500416,0.0002012137,0.001018219,0.0006449211,0.001236859,0.002911312],"category_scores_gemma":[0.0005212841,0.0001837495,0.0004160157,0.001551787,0.0004142897,0.001727301,0.0006149137,0.002277932,0.001865373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005418308,"about_ca_system_score_gemma":0.001000896,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005589083,"about_ca_topic_score_gemma":0.0007937296,"domain_scores_codex":[0.9998808,0.0000218291,0.00001727328,0.00002390323,0.00004188784,0.00001432776],"domain_scores_gemma":[0.9997688,0.00009771325,0.0000286064,0.000005629808,0.00006778909,0.00003139791],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001510126,0.00008092916,0.0002017729,0.01671194,0.00009874033,0.0003995337,0.00009612757,0.0003255907,0.002139723,0.008633552,0.06411241,0.9070486],"study_design_scores_gemma":[0.00002128755,0.0001036393,0.0005233592,0.003242477,0.00008098283,0.001355771,0.00005969478,0.00007368229,0.0002249124,0.002434631,0.9918651,0.00001442628],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006264161,0.9982153,0.00007627422,0.0005166899,0.0005158819,0.00000157737,0.000007545166,0.000004095868,0.0006000442],"genre_scores_gemma":[0.0005662382,0.9977205,0.00009850739,0.0004323579,0.0006327829,0.000003077462,0.00001694481,9.353347e-7,0.0005286348],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002911312,"threshold_uncertainty_score":0.00973928,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01865269649553489,"score_gpt":0.2995022193324443,"score_spread":0.2808495228369094,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}