{"id":"W4411465070","doi":"10.1186/s13023-025-03854-6","title":"Prevalence of vascular complications in Ehlers-Danlos syndrome: a systematic review and meta-analysis","year":2025,"lang":"en","type":"review","venue":"Orphanet Journal of Rare Diseases","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Al-Azhar University","keywords":"Ehlers–Danlos syndrome; Medicine; Meta-analysis; Observational study; Study heterogeneity; Complication; Publication bias; Systematic review; Internal medicine; Data extraction; MEDLINE; Surgery; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005290046,0.0003100781,0.004384355,0.0005446172,0.00002868766,0.00001740003,0.000611519,0.0001168519,0.0001651375],"category_scores_gemma":[0.001295437,0.0002243789,0.002453801,0.0008391924,0.00009370127,0.000007998387,0.0001644782,0.0001675446,0.000001913873],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002811762,"about_ca_system_score_gemma":0.0004300823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006227252,"about_ca_topic_score_gemma":0.000006869949,"domain_scores_codex":[0.9969726,0.0009597912,0.001204702,0.0003451351,0.0003461047,0.0001716741],"domain_scores_gemma":[0.9974542,0.0002407377,0.001050226,0.0006944463,0.0004345231,0.0001258911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.000003227151,0.0001306515,0.00006065992,0.9257548,0.07324114,0.00003471934,0.000004299808,0.000003831167,0.00000138214,0.000006406102,0.0001657786,0.0005930795],"study_design_scores_gemma":[0.0001562471,0.0001104755,0.0001569101,0.07415801,0.9207628,0.0001772613,0.00001711575,0.000001005258,0.000001630286,0.0000128249,0.004201691,0.00024397],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002450279,0.9975458,0.00009766756,0.00003974247,0.000007996364,0.001518253,0.0007484724,0.000001647474,0.00001591447],"genre_scores_gemma":[0.0006561759,0.9986067,0.0000452915,0.00004245278,0.000005598139,0.00022021,0.0001434425,0.00001678719,0.0002633544],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8515968,"threshold_uncertainty_score":0.9149908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04628743075560369,"score_gpt":0.3638829460016546,"score_spread":0.3175955152460508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}