{"id":"W4411474892","doi":"10.1016/j.jaccao.2025.05.009","title":"IGHG Recommendations for Anthracycline and Anthraquinone Cardiac Dysfunction Equivalence Ratios After Childhood Cancer","year":2025,"lang":"en","type":"review","venue":"JACC CardioOncology","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Anthracycline; Mitoxantrone; Medicine; Idarubicin; Cardiotoxicity; Daunorubicin; Epirubicin; Doxorubicin; Internal medicine; Oncology; Cancer; Chemotherapy; Breast cancer; Cytarabine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01873121,0.001767506,0.004851884,0.006883475,0.0009412263,0.00330903,0.007090229,0.007334955,0.02010389],"category_scores_gemma":[0.05184493,0.001262473,0.01294464,0.005419791,0.001127849,0.00303399,0.002737172,0.006490194,0.007249632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004917015,"about_ca_system_score_gemma":0.01394248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01859449,"about_ca_topic_score_gemma":0.0217768,"domain_scores_codex":[0.9864563,0.004905504,0.003992363,0.0006416593,0.003473529,0.000530714],"domain_scores_gemma":[0.9794566,0.00914453,0.003476728,0.0006244653,0.006782029,0.0005156003],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007503399,0.0001203312,0.0006288025,0.2093171,0.003646896,0.0002554898,0.000363484,0.0005365402,0.0008127443,0.008358498,0.325013,0.4501967],"study_design_scores_gemma":[0.001118084,0.0001402954,0.00228764,0.2707009,0.006019182,0.0002843214,0.000152736,0.0001678557,0.0003484491,0.006995767,0.7117037,0.00008109862],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007548999,0.8940663,0.004584277,0.04820557,0.01162591,0.006066575,0.01025009,0.000348682,0.02409757],"genre_scores_gemma":[0.008898131,0.8471105,0.04306757,0.06343989,0.002739247,0.01076484,0.008756845,0.0002194338,0.01500354],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02010389,"threshold_uncertainty_score":0.09906125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04402978753378907,"score_gpt":0.3948111013077006,"score_spread":0.3507813137739116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}