{"id":"W4411506827","doi":"10.51731/cjht.2025.1150","title":"Zilucoplan (Zilbrysq)","year":2025,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"Myasthenia Gravis and Thymoma","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Reimbursement; Medicine; Myasthenia gravis; Drug; Clinical trial; Thymectomy; Family medicine; Internal medicine; Pharmacology; Political science; Law","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003969111,0.00009062725,0.000369364,0.0008672481,0.0001550345,0.00001840409,0.0002008049,0.0001223706,0.00003898104],"category_scores_gemma":[0.0003794938,0.00007040409,0.00007812078,0.0003869252,0.0001406553,0.00003747251,0.00001210445,0.0004057233,0.000009340048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002621956,"about_ca_system_score_gemma":0.004208004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001648749,"about_ca_topic_score_gemma":0.001639238,"domain_scores_codex":[0.9990083,0.00002151624,0.0004421397,0.00008910197,0.00009343446,0.0003455161],"domain_scores_gemma":[0.9993217,0.00002715464,0.0001828131,0.0002318223,0.0001377261,0.00009876175],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002967594,0.00001947918,0.03304832,0.000204882,0.00007360674,0.0004369604,0.0001228631,0.000001064535,0.00006605004,0.01872838,0.04191666,0.9053521],"study_design_scores_gemma":[0.0008248804,0.0005066189,0.04445654,0.0008202952,0.00002734065,0.0008770058,0.001962423,0.000006325233,0.0006566244,0.01213109,0.9376442,0.00008662146],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4481769,0.179285,0.00106965,0.3581059,0.001413838,0.0005181759,0.00002048178,0.0002381008,0.01117192],"genre_scores_gemma":[0.9965548,0.0003118145,0.0007651134,0.001830123,0.000009933521,0.000001742288,0.000001366875,0.000006984865,0.0005181504],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9052655,"threshold_uncertainty_score":0.7464818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01491710570035115,"score_gpt":0.2962026593165034,"score_spread":0.2812855536161522,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}