{"id":"W4411509720","doi":"10.2337/dc25-1082","title":"Benefit of Semaglutide in Symptomatic Peripheral Artery Disease by Baseline Type 2 Diabetes Characteristics: Insights From STRIDE, a Randomized, Placebo-Controlled, Double-Blind Trial","year":2025,"lang":"en","type":"article","venue":"Diabetes Care","topic":"Peripheral Artery Disease Management","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Feinstein Institutes for Medical Research; Novo Nordisk; Insmed; Silence Therapeutics; Sanofi; Kowa Company; Ionis Pharmaceuticals; Regeneron Pharmaceuticals; Osiris Therapeutics; Prothena; Yale University; Medpace; Pfizer","keywords":"Semaglutide; Medicine; Type 2 diabetes; Diabetes mellitus; Internal medicine; Placebo; Randomized controlled trial; Clinical endpoint; Physical therapy; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003219951,0.0005103969,0.002305417,0.000409024,0.00006973932,0.00008188746,0.0002590446,0.0001371513,0.0003338902],"category_scores_gemma":[0.0005549148,0.0004216994,0.0005209625,0.0004717237,0.0001669965,0.0001434255,0.000137737,0.0002404145,0.00003685008],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002482128,"about_ca_system_score_gemma":0.0002291936,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003226466,"about_ca_topic_score_gemma":0.00002990566,"domain_scores_codex":[0.996677,0.0003140375,0.001348563,0.0006435891,0.0004885152,0.0005282808],"domain_scores_gemma":[0.9976361,0.0007099426,0.0003306495,0.0007206402,0.0002732045,0.0003294548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9172542,0.0007178509,0.07375008,0.001050121,0.001203428,0.00003563488,0.0004484205,0.00006466542,0.001082994,0.00006549999,0.001147607,0.003179507],"study_design_scores_gemma":[0.9678646,0.0002514133,0.01270323,0.001466798,0.001943989,4.822819e-8,0.0003400419,0.01377651,0.0005093968,0.0003172648,0.000425626,0.0004010431],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862046,0.005753332,0.00001290885,0.0004994046,0.0006405717,0.005775121,0.0005125026,0.0001020296,0.0004995854],"genre_scores_gemma":[0.9943329,0.00007765059,0.00008071572,0.001158401,0.0002517929,0.001346208,0.002287088,0.00004750316,0.0004177599],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06104685,"threshold_uncertainty_score":0.9998235,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008175544685799757,"score_gpt":0.24535417342993,"score_spread":0.2371786287441302,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}