{"id":"W4411509720","doi":"10.2337/dc25-1082","title":"Benefit of Semaglutide in Symptomatic Peripheral Artery Disease by Baseline Type 2 Diabetes Characteristics: Insights From STRIDE, a Randomized, Placebo-Controlled, Double-Blind Trial","year":2025,"lang":"en","type":"article","venue":"Diabetes Care","topic":"Peripheral Artery Disease Management","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Feinstein Institutes for Medical Research; Novo Nordisk; Insmed; Silence Therapeutics; Sanofi; Kowa Company; Ionis Pharmaceuticals; Regeneron Pharmaceuticals; Osiris Therapeutics; Prothena; Yale University; Medpace; Pfizer","keywords":"Semaglutide; Medicine; Type 2 diabetes; Diabetes mellitus; Internal medicine; Placebo; Randomized controlled trial; Clinical endpoint; Physical therapy; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001912535,0.001224893,0.003823763,0.0004021685,0.0003400139,0.001147886,0.0005778763,0.001834633,0.003241049],"category_scores_gemma":[0.002286721,0.0004171565,0.002294756,0.0004003375,0.0006360897,0.0008021963,0.0003296357,0.001756381,0.0004613211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003669581,"about_ca_system_score_gemma":0.000646837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004394464,"about_ca_topic_score_gemma":0.001210356,"domain_scores_codex":[0.9990082,0.0005395891,0.0001176328,0.0001566266,0.00009378191,0.00008416631],"domain_scores_gemma":[0.9991077,0.0003246426,0.0002629944,0.00005357076,0.00006915726,0.0001818891],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9742366,0.002289541,0.001035537,0.001637271,0.002903705,0.00003126985,0.0000370978,0.000198536,0.001169942,0.00009838214,0.0006639528,0.01569812],"study_design_scores_gemma":[0.964274,0.02804014,0.004025664,0.0001269819,0.002131504,0.00003907445,0.00002323713,0.0004052458,0.0002456072,0.0001859913,0.0004875767,0.00001492098],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9660998,0.0254139,0.0008297702,0.0009631288,0.0007880757,0.001742021,0.001269337,0.0001855404,0.002708434],"genre_scores_gemma":[0.9835652,0.007577585,0.001275325,0.001312327,0.000631398,0.002973611,0.0009571796,0.00002598449,0.001681317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003823763,"threshold_uncertainty_score":0.01084244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008175544685799757,"score_gpt":0.24535417342993,"score_spread":0.2371786287441302,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}