{"id":"W4411529908","doi":"10.1111/febs.70158","title":"Neocortical neurogenesis: a proneural gene perspective","year":2025,"lang":"en","type":"review","venue":"FEBS Journal","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Neurogenesis; Neocortex; Biology; Proneural genes; Neuroscience; PAX6; Transcription factor; Excitatory postsynaptic potential; Neurotransmission; Inhibitory postsynaptic potential; Genetics; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003423794,0.0005690272,0.0006226891,0.001624822,0.0002034171,0.0009383614,0.0005342621,0.0007884072,0.001334132],"category_scores_gemma":[0.0002833577,0.0001836999,0.0003374545,0.0008428436,0.0005099747,0.001100753,0.0005632779,0.001417829,0.0009085966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005925826,"about_ca_system_score_gemma":0.000603065,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005426356,"about_ca_topic_score_gemma":0.0006826005,"domain_scores_codex":[0.9998732,0.00001462857,0.00001976652,0.00003606999,0.00003797034,0.00001836047],"domain_scores_gemma":[0.9998172,0.00005719257,0.00003376853,0.000006975785,0.00004697941,0.00003802565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001774888,0.00006345765,0.001928444,0.012024,0.0001412643,0.001847331,0.0007173868,0.0008330873,0.05664059,0.02946069,0.02336786,0.8727984],"study_design_scores_gemma":[0.000006075214,0.0001593664,0.0038641,0.001443895,0.0001018209,0.0037686,0.0001803063,0.0001759276,0.006887446,0.004347535,0.979038,0.00002697165],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001961527,0.9927286,0.001359807,0.0009244673,0.0004407359,0.000005521581,0.00006828539,0.00002661062,0.002484458],"genre_scores_gemma":[0.005743509,0.9898375,0.0009169059,0.0005793971,0.000912653,0.000008989972,0.0001078816,0.000008954138,0.001884312],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001624822,"threshold_uncertainty_score":0.004463136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09575868817211108,"score_gpt":0.3677956482289711,"score_spread":0.27203696005686,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}