{"id":"W4411529908","doi":"10.1111/febs.70158","title":"Neocortical neurogenesis: a proneural gene perspective","year":2025,"lang":"en","type":"review","venue":"FEBS Journal","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Neurogenesis; Neocortex; Biology; Proneural genes; Neuroscience; PAX6; Transcription factor; Excitatory postsynaptic potential; Neurotransmission; Inhibitory postsynaptic potential; Genetics; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002515464,0.0008805032,0.001930136,0.0006868958,0.0006388501,0.0004918827,0.00123697,0.0003119913,0.0001783903],"category_scores_gemma":[0.002377357,0.0006850639,0.001383084,0.00104298,0.0001401722,0.0002084008,0.0004235885,0.00179395,0.0003473184],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002366577,"about_ca_system_score_gemma":0.001256397,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001323261,"about_ca_topic_score_gemma":5.459989e-7,"domain_scores_codex":[0.994318,0.00147661,0.001140615,0.001257049,0.0008635198,0.0009441918],"domain_scores_gemma":[0.9970318,0.001044704,0.0006927121,0.0005858799,0.0001543656,0.0004905068],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001546395,0.001067212,0.000002532844,0.008778631,0.0002304481,0.01770346,0.0001144096,0.00001376853,0.01338145,0.0179266,0.003018358,0.9376085],"study_design_scores_gemma":[0.0005265818,0.0005489776,0.000001879065,0.005193502,0.001814826,0.04631332,0.00001766576,0.00003198587,0.02381686,0.0004564334,0.9202044,0.001073597],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001874637,0.9939244,0.0003670927,0.0001075263,0.003113086,0.001089479,0.00008744451,0.0001609012,0.0009625744],"genre_scores_gemma":[0.00008351515,0.9967338,0.0001096061,0.0007216941,0.0009806914,0.0001014811,0.000001968605,0.0001400754,0.001127122],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9365349,"threshold_uncertainty_score":0.9995601,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09575868817211108,"score_gpt":0.3677956482289711,"score_spread":0.27203696005686,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}