{"id":"W4411531131","doi":"10.1097/tp.0000000000005441","title":"Normothermic Ex Vivo Machine Perfusion Mitigates Apoptosis in a Porcine Model of Pancreas Transplantation","year":2025,"lang":"en","type":"article","venue":"Transplantation","topic":"Organ Transplantation Techniques and Outcomes","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Toronto General Hospital; University Health Network","funders":"","keywords":"Transplantation; Pancreas transplantation; Pancreas; Ex vivo; In vivo; Medicine; Perfusion; TUNEL assay; Machine perfusion; Cold storage; Terminal deoxynucleotidyl transferase; Histopathology; Viaspan; Apoptosis; Urology; Andrology; Internal medicine; Pathology; Biology; Liver transplantation; Immunohistochemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000386407,0.0003884368,0.0004066328,0.0002539803,0.0001748502,0.0003902815,0.0002910369,0.0003234115,0.001219559],"category_scores_gemma":[0.0002241486,0.0001165183,0.0004097178,0.0001309973,0.0004060525,0.0003999259,0.0002475168,0.0008240313,0.0001501022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001628156,"about_ca_system_score_gemma":0.0003086542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002116148,"about_ca_topic_score_gemma":0.0002970333,"domain_scores_codex":[0.9998397,0.00003151396,0.00001442441,0.00003721462,0.00004456412,0.00003257913],"domain_scores_gemma":[0.9998074,0.00003212323,0.00007885387,0.00002873212,0.0000204541,0.00003238142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001496407,0.0005312836,0.0008892101,0.0001532822,0.00002320576,0.0001621947,0.00005004959,0.0005326869,0.991121,0.0001226135,0.0001145362,0.004803656],"study_design_scores_gemma":[0.0001513446,0.01737081,0.0152102,0.00008101216,0.0001263227,0.0008850303,0.0001845535,0.005350695,0.9575016,0.0003084265,0.00280388,0.00002617875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889926,0.001471914,0.008079786,0.0001131804,0.0001064293,0.000064082,0.00009545559,0.00005948791,0.001017013],"genre_scores_gemma":[0.9933426,0.001373055,0.003737414,0.00009120379,0.00003321355,0.0001257773,0.000312701,0.00001769577,0.0009664132],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001219559,"threshold_uncertainty_score":0.004079878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009714997829712007,"score_gpt":0.2648210322492191,"score_spread":0.2551060344195071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}