{"id":"W4411539481","doi":"10.1161/atv.45.suppl_1.or122","title":"Abstract Or122: SURF4-containing Classical Vesicles Mediate Apolipoprotein(a)-ApolipoproteinB Secretory Trafficking","year":2025,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Apolipoprotein B; Very low-density lipoprotein; Secretion; Intracellular; Cell biology; Endosome; Lipid-anchored protein; Lipoprotein; Biochemistry; Transfection; Endocytosis; Biology; Molecular biology; Chemistry; Cholesterol; Receptor; Autophagy; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001439543,0.0005004616,0.0002962558,0.0002090756,0.000264877,0.0004886728,0.0003786018,0.0005692884,0.01339312],"category_scores_gemma":[0.0001609172,0.0001131696,0.000338266,0.0001845712,0.0003028732,0.0003534367,0.0003983004,0.0004271049,0.003416183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004480477,"about_ca_system_score_gemma":0.0003166225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005010492,"about_ca_topic_score_gemma":0.0002833879,"domain_scores_codex":[0.9998361,0.0000207383,0.00001615703,0.00004169486,0.00005029687,0.00003492825],"domain_scores_gemma":[0.9998876,0.00001347298,0.00003624137,0.00001140398,0.00002070862,0.00003056169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005036404,0.00002283763,0.0004767194,0.0002808039,0.00001829446,0.000273021,0.00001668464,0.00004901542,0.9946514,0.0004655878,0.000875673,0.002366444],"study_design_scores_gemma":[0.0001583556,0.0004769947,0.0166605,0.00005752666,0.00009264074,0.001304889,0.0001461717,0.001483211,0.9527062,0.0004559937,0.02644123,0.00001623016],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9643083,0.006318234,0.00525817,0.001384006,0.0005896595,0.00008890081,0.005452547,0.0004439042,0.01615611],"genre_scores_gemma":[0.9527465,0.002121549,0.002549385,0.0002937336,0.0001431905,0.00007898213,0.00897987,0.00007825949,0.03300852],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01339312,"threshold_uncertainty_score":0.04480439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02023442785293029,"score_gpt":0.2747341809528021,"score_spread":0.2544997530998718,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}