{"id":"W4411539495","doi":"10.1161/atv.45.suppl_1.tu0035","title":"Abstract Tu0035: Lipoprotein(a) Induces a Proglycolytic and Proinflammatory Response in Coronary Artery and Aortic Valve Endothelial Cells, with Altered Metabolism and Reactive Oxygen Species Generation.","year":2025,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Proinflammatory cytokine; CD36; Transcriptome; Gene expression; Biology; Internal medicine; Inflammation; Endocrinology; Medicine; Receptor; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000183753,0.0004919546,0.0004007405,0.000233253,0.0002611054,0.00043149,0.0002570765,0.0005769666,0.004571073],"category_scores_gemma":[0.0001616275,0.0001462875,0.0004688923,0.0003820977,0.0003499854,0.0001825439,0.0002466309,0.0009736755,0.0008215201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003769231,"about_ca_system_score_gemma":0.0004643124,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001097726,"about_ca_topic_score_gemma":0.001266082,"domain_scores_codex":[0.9997995,0.00003600023,0.0000185885,0.0000417594,0.00004759841,0.00005657455],"domain_scores_gemma":[0.9998953,0.00001705045,0.00002502297,0.00001046051,0.00001497765,0.00003711295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001208109,0.0001024658,0.0002086705,0.0001530655,0.0000137659,0.0001011052,0.00001611817,0.00004940875,0.9955235,0.0000698826,0.0005173188,0.002036639],"study_design_scores_gemma":[0.0003326276,0.002486001,0.01664808,0.0000432979,0.00008799285,0.0005163367,0.0001402836,0.001006313,0.9706827,0.0001602233,0.007876938,0.0000191454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.983456,0.00401964,0.003287915,0.0008604108,0.0004164839,0.00007933883,0.004394025,0.0003327602,0.003153421],"genre_scores_gemma":[0.9801953,0.001995806,0.002706959,0.0006319229,0.000115776,0.000209277,0.006755959,0.00005956319,0.007329343],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004571073,"threshold_uncertainty_score":0.01529181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02601549827593896,"score_gpt":0.2616050532546531,"score_spread":0.2355895549787141,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}