{"id":"W4411539873","doi":"10.1161/atv.45.suppl_1.th0041","title":"Abstract Th0041: Endothelial Cell Activation Impairs Macrophage Efferocytosis and Promotes Inflammation.","year":2025,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Efferocytosis; MERTK; Inflammation; Cell biology; Macrophage; Phagocytosis; Apoptosis; Flow cytometry; Biology; Immunology; Medicine; In vitro; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003868647,0.0007577745,0.0004766901,0.0004358615,0.000323022,0.0004503518,0.000576063,0.0009001289,0.008864486],"category_scores_gemma":[0.0001984241,0.0002499822,0.0006082928,0.0003893267,0.0004734696,0.0002923205,0.0002120497,0.001561839,0.002302102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005060298,"about_ca_system_score_gemma":0.0004540075,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006970523,"about_ca_topic_score_gemma":0.0005632454,"domain_scores_codex":[0.9995636,0.0001073482,0.00004594312,0.00006422623,0.0001042304,0.0001145096],"domain_scores_gemma":[0.9998121,0.00002602639,0.00005291757,0.00002660393,0.00002262211,0.00005973931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001679406,0.0003262499,0.0002179994,0.0002001683,0.00002207079,0.0002335297,0.00002740401,0.0001118373,0.9936825,0.0003492042,0.0008730693,0.002276679],"study_design_scores_gemma":[0.0002790979,0.002009711,0.004360842,0.00003213615,0.00006313285,0.0009083209,0.00006375575,0.0008530222,0.9776745,0.0002006787,0.0135428,0.00001193086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9681754,0.004692307,0.006628434,0.001606337,0.0006230508,0.0001932742,0.008025724,0.0005525402,0.009502919],"genre_scores_gemma":[0.957571,0.003036487,0.004561998,0.0004850146,0.000122912,0.0004055745,0.009750465,0.0001253461,0.02394126],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008864486,"threshold_uncertainty_score":0.02965468,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01368782433550433,"score_gpt":0.2481944402051014,"score_spread":0.2345066158695971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}