{"id":"W4411550312","doi":"10.1007/978-1-0716-4654-0_7","title":"Extracellular Flux Assays for the Measurement of Glycolysis and Mitochondrial Respiration in Brain Cancer Cells","year":2025,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hamilton Health Sciences; McMaster University Medical Centre; Population Health Research Institute; McMaster University","funders":"","keywords":"Glycolysis; Extracellular; Flux (metallurgy); Respiration; Mitochondrion; Cell biology; Chemistry; Biochemistry; Biology; Metabolism; Anatomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006532099,0.0009593565,0.0006521753,0.0007407371,0.000663686,0.0006707765,0.0009583511,0.0009593341,0.001783986],"category_scores_gemma":[0.0004800103,0.000231984,0.0005030742,0.001090018,0.0004019827,0.0008277068,0.0007937427,0.002288186,0.0005362171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006104026,"about_ca_system_score_gemma":0.0004746624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001325886,"about_ca_topic_score_gemma":0.002977629,"domain_scores_codex":[0.9986854,0.0004049345,0.0001036906,0.0002430111,0.000424358,0.0001385966],"domain_scores_gemma":[0.9995379,0.000166296,0.00007158636,0.00006784787,0.00009733638,0.00005892882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002808161,0.0001177093,0.0002878698,0.000114267,0.00001869165,0.00003678511,0.00006264978,0.000225544,0.9946741,0.0008789162,0.0002214522,0.003081108],"study_design_scores_gemma":[0.00003582608,0.0002267133,0.002992378,0.00002388786,0.00003488056,0.0001500299,0.00005381683,0.003744147,0.9891769,0.0004595431,0.003080868,0.00002091705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5702229,0.008495035,0.3985102,0.0008487528,0.0006518228,0.000537853,0.00715384,0.000844799,0.01273475],"genre_scores_gemma":[0.7360705,0.006533766,0.2343566,0.0003903068,0.000150189,0.001845827,0.008261427,0.0003840909,0.01200722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001783986,"threshold_uncertainty_score":0.005968034,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02980166986668958,"score_gpt":0.3691271862955378,"score_spread":0.3393255164288482,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}