{"id":"W4411568467","doi":"10.1038/s44220-025-00449-9","title":"Gray matter volume heterogeneity by stage, site of origin and pathophysiology in schizophrenia","year":2025,"lang":"en","type":"article","venue":"Nature Mental Health","topic":"Functional Brain Connectivity Studies","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Western University","funders":"","keywords":"Pathophysiology; Gray (unit); Schizophrenia (object-oriented programming); Volume (thermodynamics); Neuroscience; Psychology; Medicine; Pathology; Psychiatry; Nuclear medicine; Physics; Thermodynamics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001748489,0.0001233542,0.0002518542,0.000117369,0.0001291719,0.00000764364,0.00007889762,0.0001040232,0.00001884283],"category_scores_gemma":[0.0001915882,0.0001120128,0.00002981585,0.0002929961,0.0001271213,0.0000726468,0.0001251595,0.0003945812,0.0000119011],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001311259,"about_ca_system_score_gemma":0.00006124537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001944772,"about_ca_topic_score_gemma":0.0003700211,"domain_scores_codex":[0.9988069,0.0002048575,0.0001973489,0.0004232801,0.0001418877,0.0002257176],"domain_scores_gemma":[0.9993415,0.000376187,0.00008036303,0.0001458437,0.00001340082,0.0000426606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0009117739,0.0004269581,0.3927867,0.0005596473,0.00001704474,0.000006675871,0.0003725485,0.000007231791,0.4581396,0.002126482,0.1401868,0.004458571],"study_design_scores_gemma":[0.003380123,0.0006396762,0.8419585,0.0001883216,0.000005710231,0.000009260958,0.0001008538,0.0002791196,0.0933083,0.002088386,0.05767607,0.0003656925],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985566,0.001370386,0.00001004541,0.01177633,0.0004613246,0.000283516,0.0003488782,0.00001756078,0.00016593],"genre_scores_gemma":[0.9762636,0.0001462733,0.0001106161,0.0227819,0.00001548057,0.00001247727,0.00001267045,0.000006785453,0.0006501313],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4491718,"threshold_uncertainty_score":0.4567751,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01014479936231335,"score_gpt":0.3058709223752851,"score_spread":0.2957261230129717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}