{"id":"W4411582115","doi":"10.3390/cells14130952","title":"Carcinogenesis Associated with Toxin Nephropathy: Proposed Mediation by Phosphate Toxicity","year":2025,"lang":"en","type":"review","venue":"Cells","topic":"Parathyroid Disorders and Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Carcinogenesis; Nephrotoxicity; Carcinogen; Toxicity; Cancer research; Cancer; Biology; DNA damage; Chemistry; Medicine; Internal medicine; Biochemistry; Genetics; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001348093,0.0005122817,0.001704329,0.0001343829,0.00009063286,0.00002874272,0.0001320754,0.0003793627,0.00004340507],"category_scores_gemma":[0.00007716301,0.0003498927,0.000305788,0.0005685025,0.00005129217,0.00004545866,0.00003722744,0.0002179175,0.0001241497],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003657847,"about_ca_system_score_gemma":0.0008654233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000369658,"about_ca_topic_score_gemma":0.00001490767,"domain_scores_codex":[0.9981496,0.0001415497,0.0004471553,0.0005374162,0.0003634587,0.0003608258],"domain_scores_gemma":[0.9987988,0.0001440641,0.0003737155,0.0004074747,0.0001087993,0.0001671818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002052548,0.003593784,0.0009609151,0.01461884,0.004133417,0.0005742172,0.0002469182,0.000001934902,0.0004461312,0.00002684172,0.1475668,0.827625],"study_design_scores_gemma":[0.004066162,0.0006340636,0.0001278933,0.006994386,0.007863509,0.0000102427,0.00002410797,0.00001261152,0.003669659,0.00001022896,0.9758455,0.0007416395],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007252055,0.9941881,0.00003172042,0.00002677441,0.0001715184,0.00206608,0.0003068717,0.00008917007,0.002394501],"genre_scores_gemma":[0.0006006067,0.9868269,0.00004558363,0.0001463977,0.00004677104,0.000145145,0.002260033,0.00005854838,0.009870036],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8282787,"threshold_uncertainty_score":0.9998953,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01698773723110289,"score_gpt":0.284594135923839,"score_spread":0.2676063986927361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}