{"id":"W4411594708","doi":"10.1152/physiol.2025.40.s1.0688","title":"Physiological media and oxygen conditions promote transcriptomic, proteomic, and functional changes in breast cancer cells","year":2025,"lang":"en","type":"article","venue":"Physiology","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"","keywords":"Transcriptome; Breast cancer; Cancer; Cancer research; Cancer cell; Biology; Cell biology; Computational biology; Physiology; Bioinformatics; Medicine; Internal medicine; Biochemistry; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001601564,0.0003571405,0.000299326,0.0002659459,0.0002476094,0.0004879178,0.0001039304,0.0002680025,0.0009280797],"category_scores_gemma":[0.0001844441,0.0001682281,0.0002956004,0.0002941506,0.0002127192,0.0002526895,0.0002741649,0.0003535953,0.0003020951],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001927129,"about_ca_system_score_gemma":0.0001926587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006733853,"about_ca_topic_score_gemma":0.001483564,"domain_scores_codex":[0.999809,0.00002441874,0.0000167243,0.00005433285,0.00005529562,0.00004036835],"domain_scores_gemma":[0.9999207,0.00001773137,0.00002399988,0.000006191178,0.00001742505,0.00001401815],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005508743,0.000007833763,0.0004293541,0.00003808662,0.000004406534,0.00002881481,0.00001669941,0.00003077995,0.9988012,0.00001130047,0.00004117768,0.0005351691],"study_design_scores_gemma":[0.00001106536,0.0002711815,0.06397576,0.00002685792,0.00005726893,0.0003085736,0.000304414,0.001000627,0.927676,0.00009800208,0.006253636,0.00001676358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986576,0.00294628,0.004643905,0.0002905371,0.00008802579,0.00005723306,0.003173206,0.0001448061,0.002079989],"genre_scores_gemma":[0.9766496,0.003702693,0.009600644,0.000614988,0.00004930837,0.0002277102,0.005076343,0.00007117463,0.004007447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009280797,"threshold_uncertainty_score":0.003104746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02113951171761309,"score_gpt":0.2774748114228973,"score_spread":0.2563352997052842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}