{"id":"W4411594708","doi":"10.1152/physiol.2025.40.s1.0688","title":"Physiological media and oxygen conditions promote transcriptomic, proteomic, and functional changes in breast cancer cells","year":2025,"lang":"en","type":"article","venue":"Physiology","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"","keywords":"Transcriptome; Breast cancer; Cancer; Cancer research; Cancer cell; Biology; Cell biology; Computational biology; Physiology; Bioinformatics; Medicine; Internal medicine; Biochemistry; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004892111,0.0001264463,0.0003541583,0.00009938693,0.00005089152,0.000003624764,0.00002953667,0.0001157005,0.0002932586],"category_scores_gemma":[0.000009590281,0.0000980014,0.00002561953,0.0000981749,0.0001830347,0.00003436044,0.00003153799,0.0001726562,0.000007325095],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001719478,"about_ca_system_score_gemma":0.00005766893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008899035,"about_ca_topic_score_gemma":0.00007214062,"domain_scores_codex":[0.999285,0.0000468328,0.0001235555,0.0002950665,0.00004488347,0.0002046819],"domain_scores_gemma":[0.9997389,0.00003282448,0.00002879201,0.00009506942,0.00003482447,0.00006964694],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000213296,0.00008864844,0.0006499906,0.00008006103,0.00005110971,0.000003731367,0.0002189795,0.000001536575,0.9953588,0.0007887603,0.001166084,0.001379022],"study_design_scores_gemma":[0.001523346,0.00005817808,0.9612127,0.00006396804,0.00008803646,0.00002224907,0.00004213661,0.00007769247,0.03168609,0.00342312,0.001706992,0.00009547328],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907863,0.001236504,0.000008012595,0.007112721,0.000220093,0.0004536439,0.00007666399,0.0000269106,0.00007921124],"genre_scores_gemma":[0.9963807,0.001269714,0.00007187185,0.001471714,0.0002421515,0.0001962829,0.00005524706,0.000007686921,0.0003045807],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9636727,"threshold_uncertainty_score":0.3996381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02113951171761309,"score_gpt":0.2774748114228973,"score_spread":0.2563352997052842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}