{"id":"W4411627008","doi":"10.1007/s11255-025-04613-z","title":"Molecular frontiers in hemodialysis: unraveling the role of membranes in gene expression, epigenetics, and inflammatory pathways","year":2025,"lang":"en","type":"review","venue":"International Urology and Nephrology","topic":"Dialysis and Renal Disease Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of Saskatchewan","funders":"","keywords":"Epigenetics; Medicine; Gene expression; Nephrology; Hemodialysis; Gene; Bioinformatics; Computational biology; Internal medicine; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007512724,0.0003957289,0.0008549344,0.0006485484,0.0003269908,0.001230057,0.0005236858,0.001107109,0.00219639],"category_scores_gemma":[0.0006654016,0.0001874352,0.0006066594,0.0006089053,0.0009794212,0.001929015,0.000816043,0.001956346,0.0004189834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005834845,"about_ca_system_score_gemma":0.001337638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005000989,"about_ca_topic_score_gemma":0.0006611024,"domain_scores_codex":[0.9997368,0.00007330018,0.00002798625,0.00004870102,0.00007820471,0.00003494111],"domain_scores_gemma":[0.9995732,0.0002488724,0.00004565986,0.00001591605,0.00008590175,0.00003043384],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0004057765,0.0001262707,0.002221471,0.0278884,0.0003457718,0.001398826,0.001173379,0.001638375,0.08628426,0.07616685,0.02812129,0.7742293],"study_design_scores_gemma":[0.00002358363,0.000331809,0.005812028,0.002636499,0.0002379467,0.002482594,0.0007216656,0.0009067067,0.01369367,0.03132784,0.9417553,0.00007041389],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003052215,0.9839994,0.003911543,0.00582759,0.0009195753,0.00001129857,0.00008586852,0.00004257997,0.002149938],"genre_scores_gemma":[0.02063501,0.9714351,0.002739029,0.002153847,0.001367169,0.00002824579,0.000132426,0.00001000036,0.001499191],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00219639,"threshold_uncertainty_score":0.007347703,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008179966878161556,"score_gpt":0.2513920807753833,"score_spread":0.2432121138972217,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}