{"id":"W4411642213","doi":"10.1146/annurev-virology-092623-111016","title":"CRISPR-Cas in the Cheese Industry","year":2025,"lang":"en","type":"review","venue":"Annual Review of Virology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"CRISPR; Biology; Streptococcus thermophilus; Cas9; Dairy industry; Genome editing; Function (biology); Computational biology; Bacteria; Biotechnology; Microbiology; Genetics; Gene; Lactic acid; Food science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006789146,0.0003133792,0.001225529,0.00009465665,0.00001852202,0.000003790919,0.0006741009,0.0007951882,0.0000351977],"category_scores_gemma":[0.0005118938,0.0002115619,0.0004260569,0.0003057081,0.00008068814,0.000001476535,0.0002061514,0.0006401751,0.00001121034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001013459,"about_ca_system_score_gemma":0.0002261031,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009975237,"about_ca_topic_score_gemma":0.0000122006,"domain_scores_codex":[0.998216,0.0003476214,0.000690792,0.0003682386,0.0001112124,0.0002661688],"domain_scores_gemma":[0.9989209,0.00007769455,0.000198413,0.0007141084,0.00005439857,0.00003452785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000004227534,0.00006880822,0.000006833227,0.1422548,0.0001090515,0.00001585275,0.00003545074,0.000001733707,0.00003235477,0.0001136351,0.01848399,0.8388733],"study_design_scores_gemma":[0.00007282665,0.0001169956,0.0000372845,0.02407115,0.0002882574,0.00005419491,0.000018188,1.261362e-7,0.00002260846,0.000007720248,0.9751465,0.0001641139],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001473969,0.9970872,0.00006351002,0.0001769492,0.0001550274,0.0006286402,0.00008404146,0.00000360887,0.001786328],"genre_scores_gemma":[0.00005578451,0.9977655,0.00004163309,0.001315333,0.0001631391,0.0001561253,0.0001965626,0.00001951296,0.0002864283],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9566625,"threshold_uncertainty_score":0.8627243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01354223700719929,"score_gpt":0.4108074305440037,"score_spread":0.3972651935368044,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}