{"id":"W4411642213","doi":"10.1146/annurev-virology-092623-111016","title":"CRISPR-Cas in the Cheese Industry","year":2025,"lang":"en","type":"review","venue":"Annual Review of Virology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"CRISPR; Biology; Streptococcus thermophilus; Cas9; Dairy industry; Genome editing; Function (biology); Computational biology; Bacteria; Biotechnology; Microbiology; Genetics; Gene; Lactic acid; Food science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000365288,0.000699946,0.0007263612,0.001379618,0.0002143105,0.0008871238,0.0006527425,0.001078051,0.003209986],"category_scores_gemma":[0.0004905795,0.000257648,0.0004885803,0.001119169,0.0003527858,0.0007964684,0.0005291352,0.001439867,0.002036382],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005984207,"about_ca_system_score_gemma":0.001010259,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001143167,"about_ca_topic_score_gemma":0.001359945,"domain_scores_codex":[0.9998179,0.00002544675,0.00002156154,0.0000378832,0.000074765,0.00002245195],"domain_scores_gemma":[0.9998413,0.00007562644,0.00002273383,0.000005926448,0.00003554498,0.00001875685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006056387,0.00003602678,0.0001562661,0.01227213,0.00006768177,0.000231655,0.00006732898,0.0007543167,0.008585586,0.007345567,0.02773153,0.9426915],"study_design_scores_gemma":[0.000007784844,0.00006332521,0.0004070245,0.001210307,0.00004838736,0.0006197842,0.0000280431,0.0001306996,0.001647072,0.001582362,0.99424,0.00001507418],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003743833,0.9948053,0.0004835627,0.0004183948,0.0003757188,0.000007220722,0.00003788764,0.00004053288,0.003456949],"genre_scores_gemma":[0.002191901,0.9947957,0.000573608,0.0003019346,0.0001800875,0.000009403246,0.000068172,0.000005097471,0.001874056],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003209986,"threshold_uncertainty_score":0.01073843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01354223700719929,"score_gpt":0.4108074305440037,"score_spread":0.3972651935368044,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}