{"id":"W4411642994","doi":"10.1016/j.esmoop.2025.105252","title":"126TiP REJOICE-Ovarian02: A phase Ib/II study of raludotatug deruxtecan (R-DXd) with other anticancer agents in participants (pts) with relapsed ovarian cancer (OC) after platinum-based chemotherapy","year":2025,"lang":"en","type":"article","venue":"ESMO Open","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; McGill University Health Centre","funders":"","keywords":"Ovarian cancer; Chemotherapy; Medicine; Internal medicine; Oncology; Platinum; Cancer; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001285446,0.001053934,0.002072447,0.0005250045,0.0003276946,0.001102237,0.0007938414,0.001309914,0.004206372],"category_scores_gemma":[0.0006646234,0.000573671,0.001238507,0.000450078,0.001009695,0.0007526662,0.0003996712,0.003069898,0.001082789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007227303,"about_ca_system_score_gemma":0.001254116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001273529,"about_ca_topic_score_gemma":0.003728761,"domain_scores_codex":[0.9996634,0.0001477564,0.00001772785,0.00005959853,0.00003242251,0.00007911713],"domain_scores_gemma":[0.9995528,0.00006001375,0.000055739,0.00004233123,0.00002283028,0.0002662057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5952611,0.139227,0.009628503,0.00175428,0.001897404,0.0004086521,0.0005171217,0.002268869,0.07048978,0.0005360958,0.004540936,0.1734703],"study_design_scores_gemma":[0.363765,0.6155054,0.01068201,0.00004886603,0.0004763672,0.000322931,0.00008928967,0.0008434799,0.004001712,0.0001365892,0.004097065,0.00003127193],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913887,0.002528698,0.0003526829,0.0003694268,0.00009637822,0.002365852,0.0009068764,0.00009458867,0.001896661],"genre_scores_gemma":[0.9868046,0.003037666,0.001485645,0.0008102231,0.0001449351,0.001751502,0.002328952,0.00003730041,0.003599208],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004206372,"threshold_uncertainty_score":0.0140717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05080459343060782,"score_gpt":0.3852990012541068,"score_spread":0.3344944078234989,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}