{"id":"W4411659005","doi":"10.5194/egusphere-2025-2083-ac1","title":"Reply on CC1","year":2025,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001965947,0.000866904,0.0009861384,0.001149218,0.002897585,0.003669891,0.002502536,0.01935316,0.2615295],"category_scores_gemma":[0.02607098,0.0004589024,0.001151804,0.0008639531,0.00169864,0.003213841,0.002537566,0.01595086,0.143395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00312021,"about_ca_system_score_gemma":0.002819513,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006463869,"about_ca_topic_score_gemma":0.008115081,"domain_scores_codex":[0.997938,0.0003747349,0.0002036989,0.0003605996,0.0007812079,0.0003418105],"domain_scores_gemma":[0.9935747,0.001986382,0.0002427983,0.0003403979,0.002911338,0.0009444355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001081927,0.000002677069,0.00003816816,0.00001387041,0.000001034244,0.00005289345,0.000009700471,0.000004020344,0.00001694157,0.0002923518,0.9971458,0.00241165],"study_design_scores_gemma":[0.000009554033,0.000007726982,0.0001868869,0.00005986466,0.000002088042,0.00008929844,0.00007223192,0.0000309092,0.00006740574,0.0004832644,0.9989819,0.000008861124],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0003752205,0.002058581,0.0003937062,0.717941,0.205711,0.0001928404,0.001191198,0.0006613439,0.07147521],"genre_scores_gemma":[0.004463913,0.00127101,0.0003136105,0.6791295,0.05704311,0.0002498452,0.0005170416,0.0003847177,0.2566272],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.2615295,"threshold_uncertainty_score":0.8749033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02244021222449885,"score_gpt":0.3187352119537362,"score_spread":0.2962949997292373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}