{"id":"W4411669052","doi":"10.1161/strokeaha.125.050397","title":"The Large Core Paradox","year":2025,"lang":"en","type":"review","venue":"Stroke","topic":"Acute Ischemic Stroke Management","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Penumbra; Medicine; Randomized controlled trial; Core (optical fiber); Observational study; Stroke (engine); Population; External validity; Infarction; Radiology; Intensive care medicine; Cardiology; Internal medicine; Myocardial infarction; Ischemia; Statistics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03571877,0.0009899008,0.002834552,0.001449534,0.001035654,0.002810874,0.002396815,0.004732963,0.01136525],"category_scores_gemma":[0.08638638,0.0004769655,0.001836331,0.001257793,0.006707694,0.005549749,0.002925094,0.01010401,0.001565126],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002081647,"about_ca_system_score_gemma":0.002285696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001353166,"about_ca_topic_score_gemma":0.0008997078,"domain_scores_codex":[0.9849725,0.008207348,0.0009042387,0.003087941,0.002404345,0.000423581],"domain_scores_gemma":[0.8615437,0.1201112,0.006474846,0.005597373,0.004543125,0.001729745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006590053,0.0004460342,0.01320082,0.003748066,0.002611369,0.001516745,0.001698746,0.002430364,0.001483506,0.4856343,0.1032912,0.3773488],"study_design_scores_gemma":[0.002634554,0.001099699,0.008454275,0.001892981,0.0009814049,0.00204747,0.0004711979,0.004453129,0.001255089,0.8837739,0.09279997,0.0001362729],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.05934496,0.1905258,0.0662685,0.5990872,0.01386702,0.0004865965,0.002531806,0.0003711543,0.06751691],"genre_scores_gemma":[0.4885952,0.03806854,0.01433692,0.421925,0.03008583,0.0008594118,0.0008406316,0.0002730966,0.005015334],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.03571877,"threshold_uncertainty_score":0.1889012,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03775815274837782,"score_gpt":0.353227267192277,"score_spread":0.3154691144438991,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}