{"id":"W4411673591","doi":"10.7554/elife.106692.1.sa3","title":"Reviewer #1 (Public review): FMRP Regulates Neuronal RNA Granules Containing Stalled Ribosomes, Not Where Ribosomes Stall","year":2025,"lang":"en","type":"peer-review","venue":"","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Azrieli Foundation","keywords":"Ribosome; Cell biology; Chemistry; RNA; Biology; Biochemistry; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.02365259,0.001557275,0.003506541,0.003315733,0.002998219,0.007378132,0.005811065,0.02350709,0.08506946],"category_scores_gemma":[0.124431,0.001273834,0.003502134,0.001950895,0.002332539,0.004540798,0.003347586,0.008895583,0.04742615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006490864,"about_ca_system_score_gemma":0.01126351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003259088,"about_ca_topic_score_gemma":0.004845755,"domain_scores_codex":[0.9858912,0.003549028,0.002280829,0.001784422,0.005527653,0.0009668715],"domain_scores_gemma":[0.832032,0.01701008,0.01005493,0.004825849,0.1275662,0.00851093],"domain_codex":null,"domain_gemma":"evaluation","domain_candidate":"evaluation","domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004423936,0.000004873735,0.00005376636,0.0008094211,0.00001526213,0.00002394256,0.00001064018,0.00001177449,0.00004069407,0.00008212899,0.9946201,0.004283145],"study_design_scores_gemma":[0.0002993729,0.00007346518,0.001298609,0.003348903,0.0001019893,0.0002435956,0.00008153231,0.0001300958,0.0001987038,0.001068932,0.9930876,0.00006721494],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"commentary","genre_scores_codex":[0.0002415422,0.01191666,0.0006926149,0.3457348,0.6305505,0.000928117,0.002860221,0.0005430723,0.006532439],"genre_scores_gemma":[0.004208993,0.01367023,0.001425578,0.4966137,0.4291688,0.003962102,0.002413829,0.0006127889,0.04792396],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.9763474,"threshold_uncertainty_score":0.2845857,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02738480187117674,"score_gpt":0.3012121932335629,"score_spread":0.2738273913623862,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}