{"id":"W4411699746","doi":"10.1002/art.43298","title":"Comparative Effectiveness of Abatacept Versus Adalimumab in Shared Epitope Positive and Negative Patients With Rheumatoid Arthritis","year":2025,"lang":"en","type":"article","venue":"Arthritis & Rheumatology","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"NIHR Newcastle Biomedical Research Centre; Bristol-Myers Squibb Canada; Versus Arthritis; Department of Health and Social Care; National Institute for Health and Care Research; Regeneron Pharmaceuticals; Pfizer; Leeds Biomedical Research Centre; Manchester Biomedical Research Centre; Bristol-Myers Squibb","keywords":"Abatacept; Adalimumab; Medicine; Rheumatoid arthritis; Internal medicine; Oncology; Physical therapy; Rituximab","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003105841,0.0005289775,0.001571686,0.0004447569,0.0002252071,0.0007047958,0.0003646851,0.0009256243,0.001847583],"category_scores_gemma":[0.005226543,0.0002653105,0.001659118,0.0003614069,0.0004400388,0.0006221395,0.0002919568,0.0007507488,0.0002771523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004569214,"about_ca_system_score_gemma":0.0003342002,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002951568,"about_ca_topic_score_gemma":0.0005311876,"domain_scores_codex":[0.9977177,0.001442848,0.0002236492,0.0002691998,0.0001987228,0.0001478741],"domain_scores_gemma":[0.9950295,0.003220598,0.0007765672,0.0001696484,0.0001129636,0.0006907893],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7655104,0.003382397,0.1662735,0.000867941,0.005491155,0.0001864439,0.0003064365,0.0009416049,0.004138805,0.0001358261,0.0003560291,0.05240947],"study_design_scores_gemma":[0.1125358,0.39371,0.476722,0.0001988427,0.006706924,0.0007363161,0.00039985,0.004357259,0.002464174,0.00056589,0.001513677,0.00008938954],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976793,0.001741606,0.0000611165,0.00006625478,0.00002689464,0.00002753056,0.00009367136,0.000004020244,0.0002996572],"genre_scores_gemma":[0.9993284,0.0002184458,0.00008386393,0.00007131837,0.00004383686,0.00002794938,0.00013745,0.000001268096,0.0000874036],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003105841,"threshold_uncertainty_score":0.01642543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00821075121769993,"score_gpt":0.2689450260916402,"score_spread":0.2607342748739402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}