{"id":"W4411724351","doi":"10.1093/jat/bkaf055","title":"Cross-reactivity in urine of 53 cannabinoid analogs and metabolites using a carboxylic acid enzyme-linked immunosorbent assay (ELISA) and homogenous enzyme immunoassay (HEIA) kit and immunalysis synthetic cannabinoid HEIA kits","year":2025,"lang":"en","type":"article","venue":"Journal of Analytical Toxicology","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Office of the Chief Medical Examiner","funders":"National Institute of Justice","keywords":"Cannabinoid; Synthetic cannabinoids; Immunoassay; Chemistry; Metabolite; Urine; Cannabinoid receptor; Cross-reactivity; Cannabinoid Receptor Agonists; Pharmacology; Chromatography; Biochemistry; Cross reactions; Receptor; Medicine; Antibody; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002996779,0.0004980105,0.002340138,0.001743054,0.0001996908,0.0001258506,0.000300984,0.0004873045,0.0001342448],"category_scores_gemma":[0.002110088,0.0004159585,0.0004238669,0.001293804,0.001363597,0.0002585357,0.0004244304,0.001371165,6.053624e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004725932,"about_ca_system_score_gemma":0.001205087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001645164,"about_ca_topic_score_gemma":0.0003539297,"domain_scores_codex":[0.9953307,0.0006951362,0.001742086,0.0006285313,0.0007002256,0.0009033186],"domain_scores_gemma":[0.9970655,0.0002709675,0.0006342641,0.000555146,0.0009398551,0.0005341996],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00275533,0.001670779,0.1144745,0.0007316644,0.002285162,0.0007962377,0.000714265,0.0001776281,0.86369,0.001264771,0.0002993842,0.01114022],"study_design_scores_gemma":[0.007816184,0.00233028,0.8795915,0.0005039165,0.002853401,0.003110586,0.0007384627,0.009629488,0.08893844,0.0008426009,0.00302535,0.0006197725],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9631016,0.02944797,0.0001480269,0.006303815,0.0001720677,0.0004455639,0.00003700821,0.00001159203,0.0003323622],"genre_scores_gemma":[0.9960086,0.002197577,0.0002005924,0.0002653542,0.0001124826,0.00001575111,0.000005817881,0.00003878987,0.001155059],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7747515,"threshold_uncertainty_score":0.9998292,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01848516932175411,"score_gpt":0.3251009828169395,"score_spread":0.3066158134951854,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}