{"id":"W4411745842","doi":"10.1186/s12974-025-03496-2","title":"CXCR4 and CXCR6 dually limit T cell entry into the polyomavirus-infected brain","year":2025,"lang":"en","type":"article","venue":"Journal of Neuroinflammation","topic":"Polyomavirus and related diseases","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; Penn State College of Medicine; National Institutes of Health; Pennsylvania Department of Health","keywords":"Neurology; Medicine; Limit (mathematics); Immunology; Neuroscience; Virology; Biology; Psychology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002823058,0.0004008722,0.000356512,0.0002413743,0.0001631453,0.0005682308,0.0003418641,0.000429601,0.001873078],"category_scores_gemma":[0.0001522675,0.0001477308,0.0002309295,0.0001000818,0.0003936668,0.0004315628,0.000307446,0.001045289,0.0003574486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003545389,"about_ca_system_score_gemma":0.0003264433,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005844348,"about_ca_topic_score_gemma":0.0009428496,"domain_scores_codex":[0.9996455,0.00006122854,0.00002822486,0.00006875738,0.00008113715,0.0001151863],"domain_scores_gemma":[0.9998888,0.00001349895,0.00003000101,0.00001657726,0.00001401461,0.00003709045],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001149268,0.00003948474,0.0001901662,0.00003782472,0.000003859725,0.00001705679,0.000008822068,0.00006496544,0.9974987,0.000253427,0.00006146735,0.001709485],"study_design_scores_gemma":[0.0000437333,0.0008781346,0.002563413,0.00001337108,0.00002036332,0.0002109783,0.00005084238,0.001928802,0.9918297,0.0001049174,0.002350365,0.000005441189],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870056,0.002950721,0.007147263,0.0002729506,0.00006448307,0.00009299422,0.0002679259,0.0001898104,0.002008205],"genre_scores_gemma":[0.9892648,0.0009869555,0.005557115,0.0001013218,0.00001853951,0.00008010316,0.0001783761,0.00001619812,0.003796502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001873078,"threshold_uncertainty_score":0.006266057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004907331657596753,"score_gpt":0.249418522369651,"score_spread":0.2445111907120542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}