{"id":"W4411746747","doi":"10.1093/humrep/deaf097.004","title":"O-004 Multi-center, external validation of a novel artificial intelligence (AI) model that predicts blastocyst PGT-A results from mature oocytes","year":2025,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"CReATe Fertility Centre","funders":"","keywords":"Blastocyst; Center (category theory); Andrology; Artificial intelligence; Gynecology; Biology; Computer science; Medicine; Embryo; Chemistry; Genetics; Embryogenesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007046212,0.000209606,0.0003557442,0.0001786325,0.000153333,0.00001910033,0.000139967,0.000232478,0.00001645211],"category_scores_gemma":[0.0008224742,0.0001875108,0.0001217038,0.0002097334,0.0002398221,0.0001660143,0.00008036535,0.0003984495,0.000008800499],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008327663,"about_ca_system_score_gemma":0.00008812836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001201726,"about_ca_topic_score_gemma":0.00002053957,"domain_scores_codex":[0.9976127,0.00007951435,0.0006545234,0.001209997,0.0002419022,0.000201333],"domain_scores_gemma":[0.9980574,0.00002884693,0.0002965578,0.00118914,0.0003746164,0.00005346875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01749859,0.004047679,0.009931272,0.0001891585,0.0002066448,0.00000422176,0.001598725,0.002917807,0.9522257,0.0009457406,0.0005037446,0.009930708],"study_design_scores_gemma":[0.001594071,0.0001861744,0.1481721,0.0003629341,0.0001413424,0.00001652655,0.0002074232,0.009902708,0.8352615,0.003855305,0.0001440126,0.0001558336],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9037561,0.0003074672,0.09267747,0.001260624,0.0008477886,0.000697512,0.0001128452,0.0001114562,0.0002287281],"genre_scores_gemma":[0.993564,0.00002568703,0.004102733,0.00006893939,0.000578426,0.00002942537,0.0003392795,0.00001407988,0.00127742],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1382409,"threshold_uncertainty_score":0.7646468,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1075085942751447,"score_gpt":0.3491069277952658,"score_spread":0.241598333520121,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}