{"id":"W4411752488","doi":"10.1093/humrep/deaf097.895","title":"P-589 Transfer outcomes of embryos with uniform whole chromosome and segmental aneuploidies diagnosed by NGS-based PGT-A: multicenter data from the International Registry of Mosaic Embryo Transfers(IRMET)","year":2025,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"CReATe Fertility Centre","funders":"","keywords":"Aneuploidy; Mosaic; Embryo transfer; Embryo; Chromosome; Biology; Medicine; Gynecology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002205033,0.0001639642,0.0003104263,0.00006633984,0.00009015961,0.000022035,0.0002677221,0.00006707438,0.00003948272],"category_scores_gemma":[0.0002301007,0.0001119632,0.00005200392,0.0001177104,0.0002963985,0.0001384624,0.00005663424,0.0001773176,0.000001010228],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003721457,"about_ca_system_score_gemma":0.00005101312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009994132,"about_ca_topic_score_gemma":0.0002732812,"domain_scores_codex":[0.9986748,0.00003521361,0.000347172,0.0005069713,0.0003097193,0.0001261227],"domain_scores_gemma":[0.9986374,0.0001842441,0.00007608807,0.0009658367,0.0000956991,0.00004077933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002734887,0.002181489,0.5416697,0.0006697766,0.001622597,0.00005001387,0.001450063,0.0001633987,0.418794,0.0002567793,0.02349708,0.006910227],"study_design_scores_gemma":[0.01154114,0.000895831,0.6719434,0.001164395,0.001045304,0.00002180492,0.002249066,0.001395799,0.3043192,0.00006008766,0.005028272,0.0003357288],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929656,0.0006300156,0.0009220105,0.003445835,0.0001568511,0.0004421434,0.001247075,0.0000424981,0.0001479539],"genre_scores_gemma":[0.996507,0.00008233521,0.0003266312,0.0001851593,0.00008360246,0.00001857047,0.002222041,0.00001519906,0.000559444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1302737,"threshold_uncertainty_score":0.4565729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02428466649615775,"score_gpt":0.2802316355224249,"score_spread":0.2559469690262671,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}