{"id":"W4411846646","doi":"10.3899/jrheum.2025-0314.30","title":"Description of Immune Checkpoint Inhibitor Associated Sicca-Like Syndrome from the Canadian Research Group of Rheumatology in Immuno-Oncology Database: A Case Series","year":2025,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McMaster University; St Joseph's Health Centre; University of British Columbia; University of Toronto; Western University; Jewish General Hospital; Dalhousie University; Research Canada; University of Calgary; Arthritis Research Centre of Canada; University of Alberta","funders":"","keywords":"Medicine; Rheumatology; Internal medicine; Sicca syndrome; Oncology; Dermatology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004245589,0.0008049449,0.0009088023,0.005688701,0.002732232,0.00133716,0.001385988,0.001195183,0.00315554],"category_scores_gemma":[0.001986667,0.0005452706,0.0008244004,0.005407103,0.0009128943,0.001006612,0.001413656,0.00101755,0.0004791677],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003020431,"about_ca_system_score_gemma":0.004970188,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.08303034,"about_ca_topic_score_gemma":0.0975811,"domain_scores_codex":[0.998117,0.00007631801,0.0003332066,0.0004439153,0.000591061,0.0004385524],"domain_scores_gemma":[0.9981666,0.0001643234,0.000627844,0.00009684621,0.0003046982,0.0006396662],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"case_report","study_design_scores_codex":[0.0001005133,0.0001113418,0.5654882,0.0002431559,0.0001021118,0.4222271,0.0007114387,0.0001321128,0.001440489,0.0002467493,0.002366896,0.006829922],"study_design_scores_gemma":[0.00002627788,0.00008156917,0.2518033,0.0001457012,0.0001073373,0.7429467,0.001147331,0.0004247082,0.0004459455,0.0001218347,0.002699523,0.00004971579],"study_design_candidate":"case_report","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850819,0.004575545,0.0007921958,0.0007001382,0.00008956996,0.0004444447,0.002888386,0.00006229753,0.005365464],"genre_scores_gemma":[0.9949491,0.001666974,0.0006083573,0.0003337778,0.0001195174,0.00004923016,0.001799121,0.00001415405,0.0004597709],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9169697,"threshold_uncertainty_score":0.1650941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03629778674810735,"score_gpt":0.3175308483439862,"score_spread":0.2812330615958789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}