{"id":"W4411847959","doi":"10.1016/s1470-2045(25)00237-2","title":"SANO trial: innovations, risks, and unanswered questions","year":2025,"lang":"en","type":"letter","venue":"The Lancet Oncology","topic":"Esophageal Cancer Research and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03643997,0.001048296,0.002909738,0.001106029,0.00368614,0.007953808,0.003786234,0.06845833,0.01005051],"category_scores_gemma":[0.1365528,0.0008152681,0.002167379,0.001624766,0.00806927,0.00828847,0.002824042,0.05645543,0.008262247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00711223,"about_ca_system_score_gemma":0.01156374,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004318184,"about_ca_topic_score_gemma":0.007571466,"domain_scores_codex":[0.9721807,0.01586758,0.002367074,0.001894417,0.006153419,0.001536761],"domain_scores_gemma":[0.8638012,0.1100027,0.0052267,0.002320107,0.008903112,0.009746186],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004930617,0.00003844976,0.000491317,0.000172866,0.00006514249,0.0003371177,0.00008614313,0.00009036896,0.00009753265,0.01281577,0.963247,0.0220652],"study_design_scores_gemma":[0.002093941,0.0001905286,0.001202672,0.001668885,0.000182179,0.0008131467,0.0004540061,0.000908545,0.0002829948,0.1049508,0.8870951,0.0001571885],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.00009938283,0.003135559,0.00004523711,0.9894537,0.00624691,0.000004135647,0.00005730604,0.000007373896,0.0009503678],"genre_scores_gemma":[0.002372019,0.002096976,0.000235275,0.9448144,0.04892191,0.00004774516,0.00004192352,0.00002178021,0.00144799],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.06845833,"threshold_uncertainty_score":0.1927153,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1437375433445489,"score_gpt":0.4464597041298731,"score_spread":0.3027221607853242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}