{"id":"W4411849427","doi":"10.1038/s41598-025-07397-5","title":"Barleria extracts containing barlerin and verbascoside boost immunity and regulate CYP450 gene in prostate cancer","year":2025,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Khon Kaen University","keywords":"Verbascoside; Prostate cancer; Immunity; Medicine; Cancer research; Biology; Traditional medicine; Bioinformatics; Cancer; Internal medicine; Immunology; Immune system; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001777487,0.0001944347,0.0002737152,0.0002109658,0.0005413811,0.0001937969,0.00009934141,0.0001233316,0.0002061094],"category_scores_gemma":[0.00008632692,0.0001877435,0.00003678229,0.0003647955,0.0005767208,0.0002257541,0.0002190513,0.0004124776,0.000003124633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007480727,"about_ca_system_score_gemma":0.0001964087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002687637,"about_ca_topic_score_gemma":0.0002684769,"domain_scores_codex":[0.9981575,0.0002093171,0.0004548088,0.0006342361,0.0001312785,0.0004128497],"domain_scores_gemma":[0.9991739,0.00008915219,0.0001870514,0.0002947478,0.00009967368,0.0001554162],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000275171,0.0001605494,0.4588287,0.0001045128,0.00009742977,0.00102421,0.001089439,0.00009771397,0.5240267,0.0001653163,0.004174019,0.009956242],"study_design_scores_gemma":[0.001688608,0.00006153151,0.6099865,0.0002366181,0.0001044831,0.000249428,0.0004166088,0.0011698,0.2131658,0.003493936,0.1689642,0.0004624662],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882619,0.004286926,0.000009972189,0.0004463887,0.004664627,0.0004267422,0.00001386691,0.00003802836,0.00185159],"genre_scores_gemma":[0.9954315,0.0005349919,0.00009381046,0.000288442,0.00003033717,0.00004684888,0.0000216815,0.00001130227,0.00354102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3108609,"threshold_uncertainty_score":0.7655956,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06323950557552281,"score_gpt":0.4021994093565906,"score_spread":0.3389599037810678,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}