{"id":"W4411856971","doi":"10.1016/j.bioactmat.2025.06.046","title":"Oral oncolytic magnetotactic bacteria elicit anti-colorectal tumor immunity and reprogram microbiota metabolism","year":2025,"lang":"en","type":"article","venue":"Bioactive Materials","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fundamental Research Funds for the Central Universities; Sichuan Province Science and Technology Support Program; Natural Science Foundation of Chongqing; Ministry of Scientific Research, Egypt; Higher Education Commision, Pakistan; Chongqing Municipal Education Commission; National Natural Science Foundation of China; Natural Science Foundation for Distinguished Young Scholars of Anhui Province; Australasian Plant Pathology Society; Canadian Fertility and Andrology Society; Bronx Council on the Arts","keywords":"Oncolytic virus; Magnetotactic bacteria; Immunity; Bacteria; Microbiology; Metabolism; Microbial metabolism; Immune system; Biology; Chemistry; Cancer research; Immunology; Biochemistry; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006175398,0.000217671,0.0001330512,0.0001198923,0.00007533163,0.0001583847,0.00007200569,0.0002177463,0.0004711699],"category_scores_gemma":[0.00005793488,0.00008624753,0.0001297294,0.00006253111,0.000120276,0.0001266842,0.0001707241,0.0002745628,0.0001232177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001750919,"about_ca_system_score_gemma":0.0001621888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002793185,"about_ca_topic_score_gemma":0.0006299985,"domain_scores_codex":[0.9999483,0.000007400413,0.000003021361,0.00000966336,0.00001521548,0.00001646066],"domain_scores_gemma":[0.9999751,0.000002115661,0.00001014756,0.00000191248,0.000004217285,0.000006552141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004758732,0.00001475478,0.00006914069,0.00003692342,0.000001867643,0.00001892469,0.000006781196,0.00004881008,0.99792,0.00006717803,0.00003357219,0.001734547],"study_design_scores_gemma":[0.00001690363,0.0003684397,0.001717406,0.000007758191,0.00001475178,0.0001337579,0.00002168127,0.0007354943,0.9933119,0.00005102433,0.003615965,0.000004743111],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900157,0.003121795,0.004282607,0.0002368301,0.0000413951,0.00005113738,0.000217682,0.00009984276,0.001932919],"genre_scores_gemma":[0.9930618,0.001550563,0.003218245,0.00006385497,0.000009290821,0.00004481692,0.0001389021,0.00001196162,0.001900516],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004711699,"threshold_uncertainty_score":0.001576245,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008951982824636698,"score_gpt":0.2927077421044392,"score_spread":0.2837557592798025,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}